Seroprevalence of Hydatidosis in People Referring to Reference Laboratory of Gorgan, Golestan Province, Northern Iran 2017
Abstract
Background: Hydatidosis is a neglected global zoonotic disease, caused by larval stage of the cestode Echinococcus granulosus in human and animal. Because of high economic and medical importance of the disease, this study was performed to find the seroprevalence of human hydatidosis in Gorgan City, Golestan Province, northern Iran.
Methods: In this cross-sectional study, blood samples were collected from people referring to Reference laboratory of Golestan University of Medical sciences in 2017. A relevant questionnaire was completed for demographic data for each person. Echinococcus IgG antibody was investigated by ELISA using native antigen B. The data were analyzed using SPSS software applying logistic regression.
Results: Overall, 612 blood samples were collected. Cut-off value was considered 0.29. Sixteen cases (2.6%) were seropositive for hydatidosis. The seroprevalence of hydatidosis was 2.3% and 4.7% among males and females, respectively. There was no statistically significant correlation between the hydatidosis and investigated variables such as sex, age, tribes, residence, education, etc.
Conclusion: The prevalence of human hydatidosis shows approximately the same range as other regions of Iran. Although due to the neighboring the Mazandaran Province reported as the highest seroprevalence of hydatidosis, we expected more rate of seropositivity.
Otero-Abad B, Torgerson PR. A systematic review of the epidemiology of echinococcosis in domestic and wild animals. PLOS Negl Trop Dis. 2013; 7(6):e2249.
Hotez PJ, Savioli L, Fenwick A. Neglected tropical diseases of the Middle East and North Africa: review of their prevalence, distribution, and opportunities for control. PLOS Negl Trop Dis. 2012; 6(2):e1475.
Thompson R. The taxonomy, phylogeny and transmission of Echinococcus. Exp Parasitol. 2008; 119(4):439-46.
Eckert J, Gemmell M, Meslin F, Pawlowski Z. WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern. World Organisation for Animal Health. 2001:56-60.
Cardona GA, Carmena D. A review of the global prevalence, molecular epidemiology and economics of cystic echinococcosis in production animals. Vet parasitol. 2013; 192(1):10-32.
WHO. Global plan to combat neglected tropical diseases 2008-2015. 2007:Geneva: World Health Organization.
Rokni M. Echinococcosis/hydatidosis in Iran. Iran J Parasitol. 2009; 4(2):1-16.
Shafiei R, Teshnizi SH, Kalantar K, Gholami M, Mirzaee G, Mirzaee F. The seroprevalence of human cystic echinococcosis in Iran: A systematic review and meta-analysis study. J Parasitol Res. 2016; 2016(1-8.
Sadjjadi SM. Present situation of echinococcosis in the Middle East and Arabic North Africa. Parasitol int. 2006; 55(S197-S202.
Harandi MF, Budke CM, Rostami S. The monetary burden of cystic echinococcosis in Iran. PLOS Negl Trop Dis. 2012; 6(11):e1915.
Rokni M. The present status of human helminthic diseases in Iran. Annals of Tropical Medicine & Parasitology. 2008; 102(4):283-95.
Hezarjaribi HZ, Fakhar M, Esboei BR, Soosaraei M, Ghorbani A, Nabyan N, Teshnizi SH. Serological evidence of human cystic echinococcosis and associated risk factors among general population in Mazandaran Province, northern Iran. Ann Med Surg. 2017; 18(1-5.
Moro P, Schantz PM. Echinococcosis: a review. Int J Infect Dis. 2009; 13(2):125-33.
Zhang W, McManus DP. Recent advances in the immunology and diagnosis of echinococcosis. FEMS Immunol Med Microbiol. 2006; 47(1):24-41.
Baharsefat M, Massoud J, Mobedi I, Farahnak A, Rokni M. Seroepidemiology of human hydatidosis in Golestan province, Iran. Iran J Parasitol. 2007; 2(2):20-4.
Rokni M, Aminian B. Evaluation of the enzyme-linked immuno-Electro Transfer Blot (EITB) technique using hydatid cyst antigens B/5 and total lgG antibodies in laboratory diagnosis of human hydatidosis. Pak J Med Sci. 2006; 22(2):127.
Ilbeigi P, Mohebali M, Kia EB, Saber-Inasab M, Aryaeipour M, Bizhani N, Rokni MB. Seroepidemiology of human hydatidosis using AgB-ELISA test in Isfahan city and suburb Areas, Isfahan province, central Iran. Iran J Public Health. 2015; 44(9):1219-24.
Gholami S, Jahandar H, Abastabar M, Pagheh A, Mobedi I, Sharbatkhori M. Echinococcus granulosus sensu stricto in dogs and jackals from Caspian sea region, northern Iran. Iran J Parasitol. 2016; 11(2):186-94.
Zibaei M, Azargoon A, Ataie-Khorasgani M, Ghanadi K, Sadjjadi S. The serological study of cystic echinococcosis and assessment of surgical cases during 5 years (2007-2011) in Khorram Abad, Iran. Niger J Clin Pract. 2013; 16(2):221-5.
Saberi-Firouzi M, Kaffashian F, Hayati E, Ghaderi A, Keshavarz H, Arshadi S, Arshadi C, Sotudehmaram M, Massarrat M, Ghalambor M. Prevalence of hydatidosis in nomadic tribes of southern Iran. Med J Islam Repub Iran. 1998; 12(2):113-8.
Harandi M, Moazezi S, Saba M, Grimm F, Kamyabi H, Sheikhzadeh F, Sharifi I, Deplazes P. Sonographical and serological survey of human cystic echinococcosis and analysis of risk factors associated with seroconversion in rural communities of Kerman, Iran. Zoonoses Public Health. 2011; 58(8):582-8.
Yousefi DH, Avizhgan M, Karimi K, Manouchehri K, Masoud J. Seroepidemiology of hydatid cyst in Chaharmahal va Bakhtiari province, Iran. Iran J Public Health. 2003; 32(2):31-3.
Asgari M, Mohebali M, Kia EB, Farahnak A, Aryaeipour M, Asadian S, Rokni MB. Seroepidemiology of human hydatidosis using AgB-ELISA test in Arak, central Iran. Iran J Public Health. 2013; 42(4):391.
Dadkhah MA, Yeganehzad M, Nadery B. Survey on hydatid cyst infestation in Sarab city (Northwest of Iran) using epidemiological and seroepidemiological criteria. J Anim Vet Adv. 2011; 10(16):2099-101.
Kasaei R, Tavalla M, Etebar H. Serological survey of Echinococcus granulosus in nomads of southwest Iran using the ELISA method during 2014-15. Infez Med. 2016; 24(1):43-7.
Shahrokhabadi R, Rahimi E, Poursahebi R. Seroepidemiological study of human hydatidosis in Rafsanjan, Kerman. Zahedan J Res Med Sci (ZJRMS). 2014; 16(4):46.
Rakhshanpour A, Harandi MF, Moazezi S, Rahimi M, Mohebali M, Mowlavi GH, Babaei Z, Ariaeipour M, Heidari Z, Rokni M. Seroprevalence of human hydatidosis using ELISA method in Qom province, central iran. Iran J Parasitol. 2012; 7(3):10-5.
Heidari Z, Mohebali M, Zarei Z, Aryayipour M, Eshraghian M, Kia E, Shodajei S, Abdi J, Rakhshanpour A, Rokni M. Seroepidemiological study of human hydatidosis in Meshkinshahr district, Ardabil Province, Iran. Iran J Parasitol. 2011; 6(3):19-25.
Tavalla M, Akhlaghi L, Ourmazdi H, Sarvi S, Razmjoo E, Shokrabi M, Siavoshi M, Beiromvand M. Using Dot-ELISA method to study the prevalence of human hydatidosis in people referred to blood transfusion center in Tehran, 2005-2006 (in Persian). Razi J Med Sci. 2010; 16(67):52-8.
Rafiei A, Hemadi A, Maraghi S, Kaikhaei B, Craig P. Human cystic echinococcosis in nomads of south-west Islamic Republic of Iran. East Mediterr Health J. 2007; 13(1):41-8.
Mirzanejadasl H, Fasihi Harandi M, Deplazes P. Serological survey of human cystic echinococcosis with ELISA method and CHF Ag, in Moghan plain, Ardabil province, Iran. Res J Biol Sci. 2008; 3(1):64-7.
Akalin S, Kutlu SS, Caylak SD, Onal O, Kaya S, Bozkurt AI. Seroprevalence of human cystic echinococcosis and risk factors in animal breeders in rural communities in Denizli, Turkey. J Infect Dev Ctries. 2014; 8(09):1188-94.
Omrani VF, Rouhani S, Kazemi B, Seyyedtabaei SJ, Kheirandish F, Rezapour M. Seroprevalence of IgG antibodies against Echinococcus granulosus by ELISA method using recombinant Agb in Lorestan Province, Western Iran. Iran J Public Health. 2017; 46(8):1132.
Fomda BA, Khan A, Thokar MA, Malik AA, Fazili A, Dar RA, Sharma M, Malla N. Sero-Epidemiological survey of human cystic echinococcosis in Kashmir, North India. PloS one. 2015; 10(4):e0124813.
Hanilou A, Badali H, Esmaeilzadeh A. Seroepidemiological study of hydatidosis in Zanjan (Islam-Abad 2002). Journal of Zanjan university of Medical Sciences and Health Services. 2004; 46(12):41-6.
Fotiou V, Malissiova E, Minas A, Petinaki E, Hadjichristodoulou C. Seroprevalence of IgG antibodies against Echinococcus granulosus in the population of the region of Thessaly, Central Greece. PLoS One. 2012; 7(5):e37112.
Campos-Bueno A, López-Abente G, Andrés-Cercadillo AM. Risk factors for Echinococcus granulosus infection: a case-control study. Am J Trop Med Hyg. 2000; 62(3):329-34.
Files | ||
Issue | Vol 14 No 3 (2019) | |
Section | Original Article(s) | |
DOI | https://doi.org/10.18502/ijpa.v14i3.1483 | |
Keywords | ||
Seroprevalence Human hydatidosis ELISA Iran |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |