Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 14 3 2019 09 18 436 443 EN Saman FATHI Student Research Committee, Arak University of Medical Sciences, Arak, Iran Reza GHASEMIKHAH Infectious Diseases Research Center (IDRC), Arak University of Medical Sciences, Arak, Iran AND Department of Parasitology and Mycology, School of Medicine, Arak University of Medical Sciences, Arak, Iran Rasool MOHAMMADI Department of Epidemiology and Biostatistics, School of Public Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran Farideh TOHIDI Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran Mitra SHARBATKHORI Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran AND Department of Parasitology and Mycology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran 2018 05 26 2019 09 18 Background: Hydatidosis is a neglected global zoonotic disease, caused by larval stage of the cestode Echinococcus granulosus in human and animal. Because of high economic and medical importance of the disease, this study was performed to find the seroprevalence of human hydatidosis in Gorgan City, Golestan Province, northern Iran. Methods: In this cross-sectional study, blood samples were collected from people referring to Reference laboratory of Golestan University of Medical sciences in 2017. A relevant questionnaire was completed for demographic data for each person. Echinococcus IgG antibody was investigated by ELISA using native antigen B. The data were analyzed using SPSS software applying logistic regression. Results: Overall, 612 blood samples were collected. Cut-off value was considered 0.29. Sixteen cases (2.6%) were seropositive for hydatidosis. The seroprevalence of hydatidosis was 2.3% and 4.7% among males and females, respectively. There was no statistically significant correlation between the hydatidosis and investigated variables such as sex, age, tribes, residence, education, etc. Conclusion: The prevalence of human hydatidosis shows approximately the same range as other regions of Iran. Although due to the neighboring the Mazandaran Province reported as the highest seroprevalence of hydatidosis, we expected more rate of seropositivity. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/2143 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/2143/968