Case Report

Splenic Infarction Secondary to COVID-19 and Malaria Co-Infection: A Case Report

Abstract

Splenic infarction is a rare complication of both malaria and COVID-19. We report a splenic infarction case due to COVID-19 and malaria co-infection. A 35‑year‑old male with no known chronical disease tested positive for both COVID-19 and malaria in Turkey in 2022. Oral artemether and lumefantrine treatment was started. On the third day of the treatment, he complained about a severe left upper quadrant pain. A repeated abdominal CT showed splenomegaly and 8 cm diameter hypodense areas throughout the spleen consistent with splenic infarction. The patient was discharged with low molecular weight heparin. A rare complication that can be seen in both diseases developed a more rigorous recommendation for anticoagulant therapy is needed for co-infections of COVID-19 with diseases that may present similar thrombotic complications.

1. Zawawi A, Alghanmi M, Alsaady I, Gattan H, Zakai H, Couper K. The impact of COVID-19 pandemic on malaria elimination. Parasite Epidemiol Control. 2020;11:e00187.
2. Wilairatana P, Masangkay FR, Kotepui KU, Milanez GJ, Kotepui M. Prevalence and characteristics of malaria among COVID-19 individuals: A systematic review, meta-analysis, and analysis of case reports. PLoS Negl Trop Dis. 2021; 15(10):e0009766.
3. Matangila JR, Nyembu RK, Telo GM, et al. Clinical characteristics of COVID-19 patients hospitalized at Clinique Ngaliema, a public hospital in Kinshasa, in the Democratic Republic of Congo: A retrospective cohort study. PLoS One. 2020; 15(12):e0244272.
4. Caglar B, Karaali R, Balkan II, Mete B, Aygun G. COVID-19 and Plasmodium ovale Malaria: A Rare Case of Co-Infection. Korean J Parasitol. 2021;59(4):399-402.
5. Hussein MIH, Albashir AAD, Elawad OAMA, Homeida A. Malaria and COVID-19: unmasking their ties. Malar J. 2020 ;19(1):457.
6. Osei SA, Biney RP, Anning AS, Nortey LN, Ghartey-Kwansah G. Low incidence of COVID-19 case severity and mortality in Africa; Could malaria co-infection provide the missing link? BMC Infect Dis. 2022 ;22(1):78.
7. Hussein R, Guedes M, Ibraheim N, Ali MM,et al . Impact of COVID-19 and malaria coinfection on clinical outcomes: a retrospective cohort study. Clin Microbiol Infect. 2022 ;28(8):1152.e1-1152.e6.
8. Hwang JH, Lee CS. Malaria-induced splenic infarction. Am J Trop Med Hyg. 2014;91(6):1094-100.
9. Kihira S, Morgenstern PF, Raynes H, Naidich TP, Belani P. Fatal cerebral infarct in a child with COVID-19. Pediatr Radiol. 2020;50(10):1479-1480.
10. Capaccione KM, Leb JS, D'souza B, Utukuri P, Salvatore MM. Acute myocardial infarction secondary to COVID-19 infection: A case report and review of the literature. Clin Imaging. 2021;72:178-182.
11. Ramanathan M, Chueng T, Fernandez E, Gonzales-Zamora J. Concomitant renal and splenic infarction as a complication of COVID-19: a case report and literature review. Infez Med. 2020;28(4):611-615.
Files
IssueVol 18 No 3 (2023) QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/ijpa.v18i3.13763
Keywords
COVID-19 Malaria Co-infection Splenic infarction

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Karakök T. Splenic Infarction Secondary to COVID-19 and Malaria Co-Infection: A Case Report. Iran J Parasitol. 2023;18(3):400-403.