Aleatory Trypanosoma cruzi Vertical Transmission in Chiapas, Mexico: A Case Report
-
Sury Antonio López-Cancino
,
Jorge Fernando Méndez-Galván
,
Mariana Soria Guerrero
,
Marcos Meneses-Mayo
,
Sergio Agustín Islas-Andrade
,
Enedina Jiménez Cardoso
Abstract
Congenital Chagas disease is considered a form of dispersion of Trypanosoma cruzi related to human migration from endemic, often rural to previously non-endemic urban areas. This fact increases the Chagas disease establishment risk inside of family members by vertical transmission pathway. Congenital Chagas disease cases in newborns could not identified by the health professional even in endemic regions. Here we present the first family cluster of Chagas disease cases from Chiapas: one of the most important endemic areas in South of Mexico, where vertical T. cruzi transmission incidence rate is ranged between 2% to 22% revealing an important public health problem. Two cases inside a family from Chiapas, México with positive antibodies against T. cruzi detected by ELISA are presented; one of them got the infection through vertical pathway. We think that congenital Chagas disease should not be ignored in a newborn born from an asymptomatic Chagas disease mother, who may transmit the parasite infection randomly.
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11. Hotez PJ, Dumonteil E, Betancourt CM, et al. An unfolding tragedy of Chagas Dis-ease in North America. PLoS Negl Trop Dis. 2013;7(10):e2300.
12. Guzmán-Bracho C, Lahuerta S, Velasco-Castrejón O. Chagas disease. First con-genital case report. Arch Med Res. 1998;29(2):195-6.
13. Campos- Valdez G, Canseco-Ávila M, Gonzales-Noriega F, et al. Transmisión Materno Fetal de Trypanosmoma cruzi, un problema de salud poco estudiado en México: Caso Chiapas. Salud Pública de México. 2016;58 (3):378 -384.
14. Cardoso EJ, Valdéz GC, Campos AC, et al. Maternal fetal transmission of Trypano-soma cruzi: a problem of public health little studied in Mexico. Exp Parasitol. 2012;131(4):425-32.
15. Olivera MA, Guillén OF, Cruz VS, et al. Serological and parasitological screening of Trypanosoma cruzi infection in mothers and newborns living in two Chagasic areas of México. Arch Med Res 2006; 37(6):774-7.
16. Bittencourt AL. Possible risk factors for vertical transmission of Chagas' disease. Rev Inst Med Trop Sao Paulo. 1992; 34(5):403–8.
17. Ramsey WJ, Schofield CJ. Control de vec-tores de la enfermedad de Chagas. Salud Publica Mex. 2003; 45(2):123-128.
18. Monroy C, Rodas A, Mejía M, et al. Epi-demiology of Chagas disease in Guatema-la: infection rate of Triatoma dimidiata, Tria-toma nitida and Rhodnius prolixus (Hemiptera, Reduviidae) with Trypanosoma cruzi and Trypanosoma rangeli (Kinetoplastida, Trypa-nosomatidae). Mem Inst Oswaldo Cruz. 2003;98(3): 305-10.
19. Di Pentima MC, Edwards MS. Enzyme-linked immunosorbent assay for IgA anti-bodies to Trypanosoma cruzi in congenital in-fection. Am J Trop Med Hyg. 1999; 60 (2):211-4.
2. WHO. Working to overcome the global impact of neglected tropical diseases. First WHO report on neglected tropical diseas-es 2010. Available from: Accessed: June 15, 2020. http://whqlibdoc.who.int/publications/2010/9789241564090_eng.pdf.
3. Salazar SP, Bucio TM, Cabrera BM, et al. Enfermedad de Chagas en México. Rev. Fac. Med. (Méx.). 2016; 59(3): 6-16.
4. Pinto-Dias JC, Amato-Neto V. [Preven-tion concerning the different alternative routes for transmission of Trypanosoma cruzi in Brazil]. Rev Soc Bras Med Trop. 2011; 2:68-72.
5. Carlier Y, Altcheh J, Angheben A, et al. Congenital Chagas disease: Updated rec-ommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women. PLoS Negl Trop Dis. 2019;13(10): e0007694.
6. Torrico F, Alonso-Vega C, Suarez E, et al. Maternal Trypanosoma cruzi infection, preg-nancy outcome, morbidity, and mortality of congenitally infected and non-infected newborns in Bolivia. Am J Trop Med Hyg. 2004;70(2):201-9.
7. Schenone H, Gaggero M, Sapunar J, et al. Congenital Chagas disease of second gen-eration in Santiago, Chile. Report of two cases. Rev Inst Med Trop Sao Paulo. 2001;43(4):231–2.
8. Schmunis GA. Epidemiology of Chagas disease in non-endemic countries: the role of international migration. Mem Inst Os-waldo Cruz. 2007; 1:75-85.
9. Carlier Y, Torrico F, Sosa-Estani S, et al. Congenital Chagas Disease: Recommen-dations for Diagnosis, Treatment and Control of Newborns, Siblings and Preg-nant Women. PLoS Negl Trop Dis. 2011; 5(10): e1250.
10. Chagas Disease in Latin America: an epi-demiological update based on 2010 esti-mates. Wkly Epidemiol Rec. 2015;90(6):33–43.
11. Hotez PJ, Dumonteil E, Betancourt CM, et al. An unfolding tragedy of Chagas Dis-ease in North America. PLoS Negl Trop Dis. 2013;7(10):e2300.
12. Guzmán-Bracho C, Lahuerta S, Velasco-Castrejón O. Chagas disease. First con-genital case report. Arch Med Res. 1998;29(2):195-6.
13. Campos- Valdez G, Canseco-Ávila M, Gonzales-Noriega F, et al. Transmisión Materno Fetal de Trypanosmoma cruzi, un problema de salud poco estudiado en México: Caso Chiapas. Salud Pública de México. 2016;58 (3):378 -384.
14. Cardoso EJ, Valdéz GC, Campos AC, et al. Maternal fetal transmission of Trypano-soma cruzi: a problem of public health little studied in Mexico. Exp Parasitol. 2012;131(4):425-32.
15. Olivera MA, Guillén OF, Cruz VS, et al. Serological and parasitological screening of Trypanosoma cruzi infection in mothers and newborns living in two Chagasic areas of México. Arch Med Res 2006; 37(6):774-7.
16. Bittencourt AL. Possible risk factors for vertical transmission of Chagas' disease. Rev Inst Med Trop Sao Paulo. 1992; 34(5):403–8.
17. Ramsey WJ, Schofield CJ. Control de vec-tores de la enfermedad de Chagas. Salud Publica Mex. 2003; 45(2):123-128.
18. Monroy C, Rodas A, Mejía M, et al. Epi-demiology of Chagas disease in Guatema-la: infection rate of Triatoma dimidiata, Tria-toma nitida and Rhodnius prolixus (Hemiptera, Reduviidae) with Trypanosoma cruzi and Trypanosoma rangeli (Kinetoplastida, Trypa-nosomatidae). Mem Inst Oswaldo Cruz. 2003;98(3): 305-10.
19. Di Pentima MC, Edwards MS. Enzyme-linked immunosorbent assay for IgA anti-bodies to Trypanosoma cruzi in congenital in-fection. Am J Trop Med Hyg. 1999; 60 (2):211-4.
| Files | ||
| Issue | Vol 16 No 4 (2021) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/ijpa.v16i4.7884 | |
| Keywords | ||
| Congenital Chagas dis-ease Trypanosoma cruzi Pregnancy Mexico | ||
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How to Cite
1.
López-Cancino SA, Méndez-Galván JF, Guerrero M, Meneses-Mayo M, Islas-Andrade SA, Cardoso E. Aleatory Trypanosoma cruzi Vertical Transmission in Chiapas, Mexico: A Case Report. Iran J Parasitol. 2021;16(4):697-702.
