Articles

Disseminated Leishmaniasis Caused by Leishmania tropica in a Puppy from Karaj, Central Iran

Abstract

A 5-month old puppy with muco-cutaneous lesions in the chin, around lips and eyes was exam­ined physically and microscopically for leishmaniasis. Muco-cutaneous lesions containing a large num­ber of amastigotes of Leishmania spp. were observed. Amastigotes were also detected in liver and spleen of the puppy. The animal was positive with Dipstick rK39 kit and high level of anti-Leishmania antibodies was detected by direct agglutination test (DAT). DNA, Using PCR-RFLP technique extracted from cultured Leishmania promastigotes and L. tropica was identified. This is the first report of concurrent mucosal and visceral involvement of L. tropica in a puppy from Iran.

Baneth, G. Leishmaniases. In: Greene CE, Infectious Diseases of the Dog and Cat .Missouri; Saunders Elsevier; 2006. p.685-698.

MohebaliM, Edrissian GhH, Nadim A , Hajjaran H,AkhoundiB , HooshmandB, Zarei Z, Arshi Sh, Mirsamadi N, Manouchehri Naeini K, Mamishi S, Sanati AA, Moshfe AA, Charehdar S, Fakhar M. Application of Direct Agg-lutination Test (DAT) for the Diagnosis and Seroepidemiological Studies of Visceral leishmaniasis in Iran. Iranian J Parasitol. 2006;1(1):15-25.

Hajjaran H, Mohebali M, Zarei Z, Edrissian GH. Leishmania tropica: Another Etiological Agent of Canine Visceral leishmaniasis in Iran. Iranian J Publ Health. 2007;36:85-88.

Mohebali M, Hajjaran H, Hamzavi Y, Mobedi I, et al. Epidemiological aspects of canine visceral leishmaniasis in the Islamic Republic of Iran. Vet Parasitol .2005; 129:243–251.

Akhoundi B, MohebaliM, Babakhan L, Edrissian GhH , Eslami MB, Keshavarz H , Malekafzali H. Rapid detection of human Leishmania infantuminfection:A comparative field study using the fast agglutination screening test and the direct agglutination test. Travel Med Inf Dis. 2010;8:305- 310.

Yaghoobi-ErshadiMR,Hanafi-Bojd AA, Javadian E,Jafari,R. A new focus of cutaneous leishmaniasis caused by Leishmania tropica. Saudi Med J. 2002;23:291-294.

Lemrani M , Nejjar R , Pratlong F. A new Leishmania tropica zymodeme — causative agent of canine visceral leishmaniasis in northern Morocco. Ann TropMed Parasitol. 2002 ;96 ( 6) : 637–638.

Stratton CW. Visceral leishmaniasis Caused by Leishmania tropica in American military personnel deployed to Southwest Asia during Operation Desert Storm. InfectDisNewsletter. 1992; 11:9-12.

Jafari S,HajiabdolbaghiM,MohebaliM, Hajjaran H and Hashemian H. Disseminated leishmaniasis caused by Leishmania tropica in HIV-positive patients in the Islamic Republic of Iran. Eastern Mediterr Health J.2010; 16 ( 3):340-343.

Edrissian GH , Shamssi S,MohebaliM, Hajjaran H, Mamishi S, Desjeux P. Evaluation of rapid “Dipstick RK39” test in diagnosis and serological surveyof visceral Leishmaniasis in humans and dogs in Iran. Arch Iranian Med. 2003; 6(1) :29-31.

Mohebali M, Taran M, Zareii Z. Rapid detection of Leishmania infantum infection in dogs: Comparative study using immunochromatographic dipstick rK39 test and direct agglutination. Vet Parasitol .2004; 121:139-145.

Harith A, Salappendel RJ, Reiter I, Knapen F, et al. Application of a direct agglutination test for detection of specific anti-Leishmania antibodies in the canine reservoir. J Clin Microbiol. 1989; 27: 2252-2257.

Nadim A, Javadian E, Mohebali M, Momeni A. Leishmania parasites and leishmaniasis.2008;3rd. Edition, Nashre Daneshgahi Press (in persian).

SantosM,Marcos R, Assunção M,Matos AJF. Polyarthritis associated with visceral leishmaniasis in a juvenile

Files
IssueVol 6 No 2 (2011) QRcode
SectionArticles
Keywords
Disseminated leishmaniasis Leishmania tropica Dog Iran

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Mohebali M, Malmasi A, Hajjaran H, Jamshidi S, Akhoundi B, Rezaei M, Janitabar S, Zarei H, Charehdar S. Disseminated Leishmaniasis Caused by Leishmania tropica in a Puppy from Karaj, Central Iran. Iran J Parasitol. 1;6(2):69-73.