Iranian Journal of Parasitology 2014. 9(2):163-168.

Canine Babesiosis in China Caused by Babesia gibsoni: A Molecular Approach.
Da-Wei Yao, Jing-Ya Jiang, Ze-Zhong Yu, Dong-Qin Yao, De-Ji Yang, Yan-Bing ZhAO


Background: To provide a point of reference to study the epidemiology and clin-ical expression of canine babesiosis in China.

Methods: A total of 30 dogs infected with canine babesiosis were evaluated by mean of clinical history, physical examination, hematological, restriction fragment length polymorphism of PCR products (PCR-RFLP) and sequencing analysis.

Result: The most prevalent clinical abnormalities were lethargy (100%), anorexia (100%), pale or icteric mucous membranes (80%), fever (70%) and dark urine (70%). Hematology parameters revealed that anemia and thrombocytopenia were the major abnormalities in blood of dogs infected with canine babesia. The results of PCR-RFLP and sequencing analysis indicated that B. gibsoni was the main species responsible for canine babesiosis cases at the time of the study in Nanjing, China.

Conclusions: The results provide valuable information for better understanding of the epidemiology of canine babesiosis in China.


Babesia gibsoni; Canine babesiosis; Epidemiology; Hematology; PCR-RFLP

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