Double-Stranded RNA Viral Infection in Tehran Trichomonas vaginalis Isolates
Abstract
Background: Trichomonas vaginalis is a pathogenic protozoon and may be contaminated with dsRNA virus called Trichomonas vaginalis virus (TVV). The viral infection is an important factor for its patho-genesis and sensitivity to metronidazole. The presence of TVV is associated with qualitative and quantitative expression of cysteine proteinases and surface immunogenic; P270. The purpose of this study was to determine TVV frequency in T. vaginalis clinical isolates in Tehran, Iran.
Methods:The 46 T. vaginalis isolates were collected from Tehran Province and cultured in TYI-S-33 culture medium. Viral RNA was extracted and RT-PCR was done.
Results:Of 46 T. vaginalis isolates, 8 isolates (17.39%) were infected with TVV-1. There was not any association between patient age and TVV- infected T. vaginalis. There were 17.39% viral infection in T. vaginalis isolates which was lower than that reported by other researchers.
Conclusion:This is the first report on T. vaginalis isolates infection by TVV-1 in Iran.
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| Issue | Vol 8 No 1 (2013) | |
| Section | Articles | |
| Keywords | ||
| Trichomonas vaginalis Viral infection dsRNA virus | ||
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