Cutaneous Leishmaniasis Lesion on the Ear from Kashan, Central Iran: A Case Report
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Abstract
Cutaneous leishmaniasis (CL) frequently occurs in many rural and urban areas of Iran. Leishmania major and L. tropica are principally two causative agents of CL in Iran. We report here a case of leishmaniasis of the ear in a 61-year-old man referred to the Reference laboratory, Kashan, central Iran, in Jan 2022. He suffered from a 2-month history of a 1×3 cm lesion on the left ear. In the microscopy examination, amastigotes forms of Leishmania spp. were observed. L. tropica was confirmed using a single PCR with species-specific primers. The patient was introduced to a physician to begin the treatment protocol. It is recommended that physicians, especially in an endemic area, investigate any atypical lesion for CL.
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2. Azim M, Khan SA, Ullah S, et al. Thera-peutic advances in the topical treatment of cutaneous leishmaniasis: A review. PLoS Negl Trop Dis. 2021; 15 (3): e0009099.
3. Alvar J, Vélez ID, Bern C, et al. Leishman-iasis Worldwide and Global Estimates of Its Incidence. PLoS One. 2012; 7(5): e35671.
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9. Shiee MR, Mohebali M, Doroodgar A, et al. A molecular and parasitological survey on cutaneous leishmaniasis patients from historical city of Kashan in Isfahan prov-ince, center of Iran. Asian Pacific J Trop Dis. 2012; 2(6):421-25.
10. Rasti S, Ghorbanzadeh B, Kheirandish F, et al. Comparison of molecular, micro-scopic, and culture methods for diagnosis of cutaneous leishmaniasis. J Clin Lab Anal. 2016; 30(5):610-15.
11. Bailey MS, Green AD, Ellis CJ, et al. Clini-cal guidelines for the management of cuta-neous leishmaniasis in British military per-sonnel. J R Army Med Corps. 2005; 151(2):73-80.
12. Aransay A, Scoulica E, Tselentis Y. Detec-tion and identification of Leishmania DNA within naturally infected sand flies by seminested PCR on minicircle kinetoplastic DNA. Appl Environ Microbiol. 2000; 66 (5): 1933–38.
13. Ghatee MA, Taylor WR, Karamian M. The geographical distribution of cutaneous leishmaniasis causative agents in Iran and its neighboring countries, a review. Front Public Health. 2020; 8:11.
14. Ahmadi NA, Ghafarzadeh M, Jalaliga-loosang A, et al. An epidemiological study of cutaneous leishmaniasis with emphasis on incidence rate in Kashan, Isfahan prov-ince. J Ilam Univ Med Sci. 2013; 21(2): 1 - 9.
15. Hajjaran H, Mohebali M, Akhavan AA, et al. Unusual presentation of disseminated cutaneous leishmaniasis due to Leishmania major: case reports of four Iranian patients. Asian Pacific J Trop Med. 2013; 6(4): 333-6.
16. Mosayebi M, Mohebali M, Farazi A, et al. Leishmaniasis Caused by Leishmania major on the Glans Penis: A Case Report. Iran J Parasitol. 2019;14(3): 472-476.
17. Bahmani M, Shamsi M, Naserifar R, et al. A rare case report of extensive cutaneous Leishmaniasis lesions on ear from Dehloran city, West of Iran and the treat-ment process. Int J Adv Bio Res. 2017; 8(3):1747-49.
18. Goldin H, Kohen S, Taxy J, et al. Leishma-nia tropica infection of the ear treated with photodynamic therapy. JAAD Case Rep. 2020; 6(6):514-17.
19. Meireles CB, Maia LC, Soares GC, et al. Atypical presentations of cutaneous leish-maniasis: a systematic review. Acta Trop. 2017; 172:240-54.
2. Azim M, Khan SA, Ullah S, et al. Thera-peutic advances in the topical treatment of cutaneous leishmaniasis: A review. PLoS Negl Trop Dis. 2021; 15 (3): e0009099.
3. Alvar J, Vélez ID, Bern C, et al. Leishman-iasis Worldwide and Global Estimates of Its Incidence. PLoS One. 2012; 7(5): e35671.
4. Sabzevari S, Teshnizi SH, Shokri A, et al. Cutaneous leishmaniasis in Iran: A sys-tematic review and meta-analysis. Microb Pathog. 2021; 152: 104721.
5. Burza S, Croft SL, Boelaert M. Leishmani-asis. Lancet. 2018; 392 (10151): 951–70.
6. Marra F, Chiappetta MC, Vincenti V. Ear, nose and throat manifestations of muco-cutaneous Leishmaniasis: a literature re-view. Acta Biomed. 2014; 85 (1): 3-7.
7. Davoodi T, Khamesipour A, Shahabi S, et al. Geographical distribution and molecular epidemiology of cutaneous leishmaniasis in Fars Province, southern Iran. Environ Sci Pollut Res. 2022; 29: 4024–32.
8. Piroozi B, Moradi G, Alinia C, et al. Inci-dence, burden, and trend of cutaneous leishmaniasis over four decades in Iran. Iran J Public Health. 2019; 48(Supple 1):28–35.
9. Shiee MR, Mohebali M, Doroodgar A, et al. A molecular and parasitological survey on cutaneous leishmaniasis patients from historical city of Kashan in Isfahan prov-ince, center of Iran. Asian Pacific J Trop Dis. 2012; 2(6):421-25.
10. Rasti S, Ghorbanzadeh B, Kheirandish F, et al. Comparison of molecular, micro-scopic, and culture methods for diagnosis of cutaneous leishmaniasis. J Clin Lab Anal. 2016; 30(5):610-15.
11. Bailey MS, Green AD, Ellis CJ, et al. Clini-cal guidelines for the management of cuta-neous leishmaniasis in British military per-sonnel. J R Army Med Corps. 2005; 151(2):73-80.
12. Aransay A, Scoulica E, Tselentis Y. Detec-tion and identification of Leishmania DNA within naturally infected sand flies by seminested PCR on minicircle kinetoplastic DNA. Appl Environ Microbiol. 2000; 66 (5): 1933–38.
13. Ghatee MA, Taylor WR, Karamian M. The geographical distribution of cutaneous leishmaniasis causative agents in Iran and its neighboring countries, a review. Front Public Health. 2020; 8:11.
14. Ahmadi NA, Ghafarzadeh M, Jalaliga-loosang A, et al. An epidemiological study of cutaneous leishmaniasis with emphasis on incidence rate in Kashan, Isfahan prov-ince. J Ilam Univ Med Sci. 2013; 21(2): 1 - 9.
15. Hajjaran H, Mohebali M, Akhavan AA, et al. Unusual presentation of disseminated cutaneous leishmaniasis due to Leishmania major: case reports of four Iranian patients. Asian Pacific J Trop Med. 2013; 6(4): 333-6.
16. Mosayebi M, Mohebali M, Farazi A, et al. Leishmaniasis Caused by Leishmania major on the Glans Penis: A Case Report. Iran J Parasitol. 2019;14(3): 472-476.
17. Bahmani M, Shamsi M, Naserifar R, et al. A rare case report of extensive cutaneous Leishmaniasis lesions on ear from Dehloran city, West of Iran and the treat-ment process. Int J Adv Bio Res. 2017; 8(3):1747-49.
18. Goldin H, Kohen S, Taxy J, et al. Leishma-nia tropica infection of the ear treated with photodynamic therapy. JAAD Case Rep. 2020; 6(6):514-17.
19. Meireles CB, Maia LC, Soares GC, et al. Atypical presentations of cutaneous leish-maniasis: a systematic review. Acta Trop. 2017; 172:240-54.
| Files | ||
| Issue | Vol 18 No 1 (2023) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/ijpa.v18i1.12390 | |
| Keywords | ||
| Leishmania Ear Iran | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Hooshyar H, Rasti S, Rostamkhani P. Cutaneous Leishmaniasis Lesion on the Ear from Kashan, Central Iran: A Case Report. Iran J Parasitol. 2023;18(1):119-124.
