Disseminated Strongyloidiasis in a Patient with Membranoproliferative Glomerulonephritis- Case Report
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Abstract
Strongyloides stercoralis (SS) is a unique nematode with an auto infective cycle, so that it completes its life cycle within the human host and can live there for many years. In immunocompromised patients, infection can cause Strongyloides hyperinfection syndrome (S.H.S) that is associated with serious morbidity and mortality. As vari-ous infections are one of the leading causes of membranoproliferative glomerulo-nephritis (MPGN), we should consider subclinical strongyloidiasis as a possible underlying disease, especially in endemic areas. Here we describe a case of strongy-loidiasis following immunosuppressive therapy for MPGN, the diagnosis of which was made, only a few hours before death, by stomach biopsy.
Hsieh YP, Wen YK, Chen ML. Minimal change nephrotic syndrome in association with strongyloidiasis. Clin Nephrol. 2006; 66:459–63.
Morimoto J, Kaneoka H, Sasatomi Y, Sato YN, Murata T, Ogahara S. Disseminated strongy-loidiasis in nephrotic syndrome. Clin Nephrol. 2002;57:398–401.
Sathe PA, Madiwale CV. Strongyloidiasis hy-perinfection in a Patient with membranoprolif-erative glomerulonephritis. J Postgrad Med. 2006;52:221–2.
Paul B. Keiser, Thomas B. Nutman Strongyloides stercoralis in the. Immunocompromised Popula-tion. Clin Microbiol Rev. 2004, 17(1):208.
Miyazaki M, Tamura M, Kabashima N, et al. Minimal change nephrotic syndrome in a pa-tient with strongyloidiasis. Clin Exp Nephrol. 2010,14:367–71.
Jalali M, Rezaiian M, Rokni MB. Relationship between serum IgE level and intestinal para-sites. Iran J Public Health. 2004;33:28-32.
Farahnak A. Survey on prevalence of parasites in the central area of Khuzestan. Medical Jour-nal of Tabriz University of Medical Scienc-es,2001;49:57-62.
Husni RN, Gordon SM, Longworth DL, Adal KA. Disseminated Strongyloides Stercoralis infec-tion in an immunocompetent patient. Clin In-fect Dis.1996, 23:663-4
Tanton DD, Durning S, Chambers S. Pulmo-nary hyperinfection with Strongyloides Stercoralis in an immunocompetent patient. J Gen Intern. Med.2002, 17:72–73.
Buchwald D, Lam M, Hooton TM. Prevalence of intestinal parasites and association with symptoms in Southeast Asian refugees. J Clin Pharm Ther. 1995; 20:271–5.
Genta RM. Dysregulation of strongyloidiasis: a new hypothesis. Clin Microbiol Rev. 1992. 5:345–355.
Siddiqui AA, Berk SL. Diagnosis of Strongyloides Stercoralis infection. Clin Infect Dis. 2001. 33:1040–1047.
Olsen A, van Lieshout L, Marti H, et al. Stron-gyloidiasis—the most neglected of the neglect-ed tropical diseases? Trans R Soc Trop Med Hyg. 2009:103(10):967-72.
Gill GV, Beeching NJ, Khoo S, et al. A British Second World War veteran with disseminated strongyloidiasis. Trans R Soc Trop Med Hyg. 2004; 98:382–6.
H Moghaddassani, Mirhendi H, Hosseini M, Rokni MB, Mowlavi Gh, Kia Eb. Molecular Diagnosis of Strongyloides Stercoralis Infection by PCR Detection of Specific DNA in Human Stool Samples. Iran J Parasitol. 2011; 6: 23-30.
Cruz T, Reboucas G, Rocha H. Fatal strongy-loidiasis in patients receiving corticosteroids. N Engl J Med. 1966;275:1093–6.
Rogers WA, Jr, Nelson B. Strongyloidiasis and malignant lymphoma: ―Opportunistic infec-tion‖ by a nematode. JAMA. 1966;195:685–7.
Igra-Siegman Y, Kapila R, Sen P et al. Louria Syndrome of Hyperinfection with Strongyloides Stercoralis. Oxford J Med Clin Infec Dis.1981, 3 :397-407.
Boonpucknavig V, Soontornniyomkij V. Pa-thology of renal diseases in the tropics. Semin Nephrol. 2003;23:88–106.
Seet RC, Lau LG, Tambyah PA. Strongyloides hyperinfection and hypogammaglobulinemia. Clin Diagn Lab Immunol. 2005;12:680–2.
Copelovitch L, Sam Ol O, Taraquinio S, Chanpheaktra N. Childhood nephrotic syn-drome in Cambodia: an association with gastrointestinal parasites. J Pediatr. 2010; 156:76–81.
Gill DS, Fonseca VA, Barradas MA, Balliod R, Moorhead JF, Dandona P. Plasma histamine in patients with chronic renal failure and nephrot-ic syndrome. J Clin Pathol. 1991;44:243–5.
Bheekha-Escura R, MacGlashan DW, Lang-don JM, MacDonald SM. Human recombinant histamine-releasing factor activates human eo-sinophils and the eosinophilic cell line, AML14–3D10. Blood. 2000;96:2191–8.
Toyabe S, Kaneko U, Hara M, Uchiyama M. Expression of immunoglobulin E-dependent histamine-releasing factor in idiopathic ne-phrotic syndrome of childhood. Clin Exp Im-munol. 2005;142:162–6.
Zali M R, Jafari Mehr A, Rezaian M, Meamar A R, Vaziri S, Mohraz M. Prevalence of Intes-tinal Parasitic Pathogens among HIV-Positive Individuals in Iran. Jpn J Infect Dis. 2004, 57: 268-270.
Kia EB, Rahimi H, Mirhendi H, et al. A case of fatal strongyloidiasis in a patient with chronic lymphocytic leukemia and molecular character-ization of the isolate. Korean J Parasitol. 2008,46: 261-263
Mahmoodi Nesheli H, Galini Moghaddam T, Zahedpasha Y, et al. Acute Lymphoblastic Leukemia with Eosinophilia and Strongyloides Stercoralis Hyperinfection. Iran J Pediatr. 2011, 21: 549-552.
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| Issue | Vol 10 No 1 (2015) | |
| Section | Articles | |
| Keywords | ||
| Hyperinfection Immunosuppression Membranoproliferative glomerulonephritis Strongyloides stercoralis | ||
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