Case Report

The Effect of Preoperative Albendazole Treatment on Intra-muscular Cyst Structure in a Patient with Simultaneous Cystic Echinococcusis of Liver and Vastus Lateralis Muscle

Abstract

We report a 44-years-old woman with cystic echinococcosis (CE) who presented with simultaneous involvement of liver and vastus lateralis muscle to Istanbul University-Cerrahpasa, Istanbul, Turkey in 2020. Although she underwent surgery for the liver, the intramuscular mass was ignored. While the patient was under post-operative albendazole treatment, she was investigated for the mass on her right thigh which was excised later. The comparison of magnetic resonance imaging before and after albendazole treatment showed that albendazole eliminated the intramuscular vesicle structures by accelerating the degeneration process of the cyst. The comparison of pathology samples sent from both liver and intramuscular CE also revealed that the albendazole has left the laminar membrane intact, degenerate the germinative membrane, thereby reducing the intra-vesicle pressure and also caused the scolex structures to disappear. To the best of our knowledge, this is the first paper to report the effect of preoperative albendazole treatment on the structure of intramuscular CE.

1. Falagas ME, Bliziotis IA. Albendazole for the treatment of human echinococcosis: A review of comparative clinical trials. Am J Med Sci. 2007;334(3):171–9.
2. Kurz K, Schwabegger A, Schreieck S, Zelger B, Weiss G, Bellmann-Weiler R. Cystic echinococcosis in the thigh: a case report. Infection. 2019;47(2):323–9.
3. Stojkovic M, Rosenberger K, Kauczor HU, Junghanss T, Hosch W. Diagnosing and Staging of Cystic Echinococcosis: How Do CT and MRI Perform in Comparison to Ultrasound? PLoS Negl Trop Dis. 2012;6(10).
4. Usluer O, Kaya SO, Samancilar O, Ceylan KC, Gursoy S. The effect of preoperative albendazole treatment on the cuticular membranes of pulmonary hydatid cysts: Should it be administered preoperatively? Kardiochir Torakochirurgia Pol. 2014;11(1):26–9.
5. Singh S, Kalra G, Gupta V, Gupta S. Pri-mary Giant Hydatid Cyst of Lumbar Paraspinal Muscles. World Neurosurg. 2020;141:240–4.
6. Merad Y, Derrar H, Zeggai A, Belkacemi M, Belmokhtar Z, Adjmi-Hamoudi H. A rare primary hydatid cyst of the psoas muscle in a rural setting: A case presenta-tion. Ann Med Surg. 2020;59:86–8.
7. Manouras A, Genetzakis M, Lagoudiana-kis EE, et al. Intact germinal layer of liver hydatid cysts removed after administration of albendazole. Neth J Med. 2007;65(3):112–6.
8. Dudkiewicz I, Salai M, Apter S. Hydatid cyst presenting as a soft-tissue thigh mass in a child. Arch Orthop Trauma Surg. 1999;119(7–8):474–5.
9. von Sinner W, te Strake L, Clark D, Sharif H. MR imaging in hydatid disease. Am J Roentgenol. 1991;157(4):741–5.
Files
IssueVol 17 No 1 (2022) QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/ijpa.v17i1.9030
Keywords
Echinococcus Intramuscular Hydatid cyst Albendazole Preoperative
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Ozsahin MK, Karaismailoglu B, Davulcu CD, Sahin E, Hız M. The Effect of Preoperative Albendazole Treatment on Intra-muscular Cyst Structure in a Patient with Simultaneous Cystic Echinococcusis of Liver and Vastus Lateralis Muscle. Iran J Parasitol. 2022;17(1):96-100.