Original Article

Situation of Asymptomatic Malaria among Iranian Native and Afghan and Pakistani Immigrants in a Malarious Area under the National Malaria Elimination Program of Iran


Background: This study was designed to detect, if there are asymptomatic malaria infections amongst native and immigrant population from Afghanistan and Pakistan countries in Sistan & Baluchistan Province of Iran, where is under the national malaria elimination program.

Methods: This cross-sectional study was performed among native individuals and resident immigrants in the southeastern province of Sistan & Baluchistan from May 2016 to Jul 2017. A total of 271 individuals were considered in this cross- sectional study based on microscopical method, Rapid Diagnostic Tests (RDTs) and PCR techniques. Out of 271 native and immigrant participants 140 (52%) and 131 (48%) were male and female, respectively.

Results: None of the prepared samples was diagnosed as malaria positive case when was considered via above mentioned three techniques.

Conclusion: Neither native nor immigrant individuals had asymptomatic malaria, hinting that national malaria elimination program is performed according to planned schedule in the studied areas

1. Warrel DA, Gilles HM. Essential Malariology. Ox-ford University press Inc, 2003; Fourth edition, Ar-nold, London.
2. Niang M, Thaim LG, Sane R, et al. Substantial asymptomatic submicroscopic Plasmodium carriage during dry season in low transmission areas in Sen-egal: Implication for malaria control and elimination. PLoS One. 2017; 12(8): e0182189
3. Lin JT, Saunders DL, Meshnick SR. The role of submicroscopic parasitemia in malaria transmission: What is the evidence? Trends Parasitol. 2014;30(4):183-190.
4. World health organization. World malaria report 2019. https://www.who.int/publications-detail-redirect/9789241565721
5. Ehtesham R, Fazeli A, Raeisi A, et al. Detection of mixed-species infections of Plasmodium falciparum and Plasmodium vivax by nested PCR and rapid diag-nostic tests in southeastern Iran. Am J Trop Med Hyg. 2015; 93(1):181-5.
6. Nateghpour M, Akbarzadeh K, Farivar L, et al. Detection of asymptomatic malaria infection among the Afghani immigrant population in Iranshahr district of southeastern Iran. Bull Soc Pathol Exot. 2011;104(4):321-3.
7. Zoghi S, Mehrizi AA, Raeisi A, et al. Survey for asymptomatic malaria cases in low transmission set-tings of Iran under elimination programme. Malar J. 2012; 11:126.
8. World Health organization. Basic malaria micros-copy-part I: Learner’sguide. Secondedition. 2010. https://www.who.int/malaria/publications/atoz/9241547820/en/
9. World Health Organization. Malaria Diagnosis: New Perspectives. WHO/CDS/RBM/2000.14, Geneva. 2000.
10. Amirshekari MB, Nateghpour M, Raeisi A, et al. Determination of asymptomatic malaria among Af-ghani and Pakistani immigrants and native popula-tion in south of Kerman province, Iran. Iran J Par-asitol.2016;11(2):247-252.
11. Pirahmadi S, Zakeri S, Raeisi A. Absence of Asymptomatic Malaria Infection in a Cross-sectional Study in Iranshahr District, Iran under Elimination Programmes. Iran J Parasitol. 2017;12(1):90-100.
12. Leoratti FMS, Durlacher RR, Lacerada MVG, et al. Pattern of humoral immune response to Plasmodium falciparum blood stages in individuals presenting dif-ferent clinical expressions of malaria. Malar J.2008;7:186.
13. Turki H, Zoghi S, Mehrizi A, et al. Absence of asymptomatic malaria infection in endemic area of Bashagard district, Hormozgan province, Iran. Iran J Parasitol. 2012;7(1):36-44.
14. Fernando SD, Abeyasinghe RR, Galappaththy GN, et al. Absence of asymptomatic malaria infections in previously high endemic areas of Sri Lanka. Am J Trop Med Hyg. 2009; 81(5):763-7.
15. Nateghpour M, Khojasteh HA, Keshavarz H, et al. Comparison of microscopical examination and semi-nested multiplex polymerase chain reaction in diagnosis of Plasmodium falciparum and P. vivax. East Mediterr Health J. 2011; 17(1):51-5.
16. Turki H, Raeisi A, Malekzadeh K, et al. Efficiency of nested-PCR in detecting asymptomatic cases toward malaria elimination program in an endemic area of Iran. Iran J Parasitol. 2015;10(1):39-45.
17. Osorio L, Todd J, Bradley D. [Absence of asymp-tomatic malaria in schoolchildren of Quibdó, Chocó]. Biosmedica. 2004;24(1):13-9.
18. Worku L, Damtie D, Endris M, et al. Asymptomat-ic malaria and associated risk factors among school children in sanja town, Northwest Ethiopia. Int Sch Res Notices. 2014; 2014: 303269
IssueVol 15 No 4 (2020) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/ijpa.v15i4.4858
Asymptomatic malaria Malaria elimination Immigrants Iran

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
ASKARI S, NATEGHPOUR M, MOTEVALLI HAGHI A, FARIVAR L, RAEISI A, MOHEBALI M. Situation of Asymptomatic Malaria among Iranian Native and Afghan and Pakistani Immigrants in a Malarious Area under the National Malaria Elimination Program of Iran. Iran J Parasitol. 2020;15(4):530-536.