The Multiple Forms of Leishmania major in BALB/C Mice Lung in Iran
Abstract
Cutaneous leishmaniasis is one of the most important parasitic diseases, which are endemic in different parts of Iran. Leishmania major and L. tropica are the primary causative agents of this disease. The aim of the present study was to detect the multiple forms of L. major in lung. Ppromastigotes of L. major at stationary phase were injected to BALB/c mice. After 60 days, the different forms of Leishmania parasites were checked in lung tissue. Promastigote and amastigote forms of Leishmania parasites were detected.
Murray HW, Berman JD, Davies CR, Saravia NG. Advances in leishmaniasis. Lancet. 2005; 4: 1561- 1577.
Bailey MS, Lockwood DNJ. Cutaneous leishmaniasis. Clin Dermatol. 2007; 25: 203–211.
Jafari M, Sherbazo SH, Nourozi M. Study ofDNA damage in Leishmania infected skin cells. FEBS J. 2008; 275 (Supple. 1): 270.
Yaghoobi R, Maraghi S, Bagherani N. Cutaneous leishmaniasis with unusual presentation. Iranian J Parasitol. 2009; 4; 67-69.
Ahmadi Yazdi C, Narmani MR, Sadri B. Cutaneous leishmaniasis in Iran. Int J Infec Dis. 2003; 3:1.
Amini M, Nahrevanian H, Farahmand M. Pathogenicity variations of vusceptibility and resistance to Leishmania major MRHO/IR/75/ER strain in BALB/c and C57BL/6 mice. Iranian J Parasitol, 2008; 3: 51-59.
Sacks D, Noben-Trauth N. The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol. 2002; 2: 845-858.
Mehrani H, Mahmoodzadeh A, Sherbazo SH, Jafari M. Study of enzyme activities in Leishmania major secretory and excretory products of Leishmania major. Daneshvar Medicine. 2005; 56: 57-63 [Persian].
Habibi P, Sadjjadi SM, Owji M,Moattari A, Sarkari B, Naghibalhosseini F, Hatam GR, Kazemian S. Characterization of in vitro cultivated amastigote like of Leishmani major: A Substitution for in Vivo Studies. Iranian J Parasitol. 2008; 3: 6-15.
Hatam GR, RezanezhadH, Motazedian MH, Sarkari B. In vitro infectivity of Leishmania major isolated from patients with different clinical forms of cutaneous leishmaniasis and its association with parasite zymodems. Iranian J Parasitol. 2009; 4: 52-60.
Mohebali M, Malmasi A, Hajjaran H, Jamshidi S, Akhoundi B, Rezaei M, Janitabar S, Zarei H, Charehdar S. Disseminated leishmaniasis caused by Leishmania tropica in a puppy from Karaj, Central Iran. Iranian J Parasitol. 2011; 6: 69-73.
Jafari S, Hajiabdolbaghi M, Mohebali M, Hajjaran H and Hashemian H. Disseminated leishmaniasis caused by Leishmania tropica in HIV-positive patients in the Islamic Republic of Iran. Eastern Mediterr Health J. 2010; 16: 340- 343.
Altes J, Salas A, Riera M, Udina M, Galmes A, Balanzat J, Ballesteros A, Buades J, Salva F, Villalonga C. Visceral leishmaniasis: another HIV-associated opportunistic infection? Report of eight cases and review of the literature. AIDS. 1991; 5: 201–207.
Holzmuller P, Hide M, Sereno D, Lemesre JL. Leishmania infantum amastigotes resistant to nitric oxide cytotoxicity: Impact on in vitro parasite developmental cycle and metabolic enzyme activities. Infection, Genetics and Evolution. 2006; 6: 187–197.
Reybier K, Ribauta C, Costea A, Launay J, Fabre PL, Nepveu F. Characterization of oxidative stress in Leishmaniasis-infected or LPS-stimulated macrophages using electrochemical impedance spectroscopy. Biosensors and Bioelectronics. 2010; 25: 2566–2572. 16. Bosca L, Zeini M, Traves PG, Hortelano, S. Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophages function and fate. Toxicology. 2005; 208: 249-258.
Zilberstein D, Shapira M. The role of pH and temperature in the development of Leishmania parasites. Annu Rev Microbiol. 1994; 48:449-70.
| Files | ||
| Issue | Vol 7 No 2 (2012) | |
| Section | Articles | |
| Keywords | ||
| Multiple forms Leishmania major BALB/c mice Lung | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
