Prevalence of Schistosoma intercalatum and S. haematobium Infection among Primary Schoolchildren in Capital Areas of Democratic Republic Of São Tomé and Príncipe, West Africa
AbstractBackground: A parasitological survey of Schistosoma haematobium and S. intercalatum infection among primary schoolchildren in capital area of Democratic Republic of São Tomé and Príncipe (DRSTP) was undertaken.Methods: Subjects with positive infection were confirmed by the detection of S. haematobium ova in the urine or S. intercalatum ova in the stool by using centrifugation concentration or merthiolate-iodine-formalin concentration method. Totally, 252 urine and stool samples, respectively, were obtained from apparently healthy schoolchildren, of which 121 from boys (9.8 ± 1.4 yr) and 131 from girls (9.7 ± 1.3 yr).Results: None of participating schoolchildren were found having S. haematobium ova in the urinary specimen. While, among 4 primary schools studied, only schoolchildren from Saint Marçal were detected with S. intercalatum ova in the fecal specimen, making the overall prevalence of S. intercalatum infection among schoolchildren was 2.4% (6/252) and girls had insignificantly higher prevalence (3.1%, 4/131) than that (1.7%, 2/121) in boys (χ2 = 0.5, P = 0.5).Conclusion: Water control and sanitation as well as snails eliminated by molluscicides are urgently needed to reduce S. intercalatum infection in DRSTP inhabitants.
Steinmann P, Keiser J, Bos R, Tanner M, Utzinger J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk . Lancet Infect Dis. 2006; 6:411-425.
Hotez PJ, Kamath A. Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden. PLoS NeglTrop Dis. 2009; 3:e412.
Them Tchuente´ LA, Southgate VR, Jourdane J, Vercruysse J. Schistosoma intercalatum: anendangered species in Cameroon? Trends Parasitol. 2003;19: 389-93.
Southgate VR, Bray RA. Medical helminthology. In: Cook GC, Zumla AI, eds. Manson’s tropical diseases. London: Saunders; 2003. p. 1649-1716.
Almeda J, CorachanM, Sousa A,Ascaso C, Carvalho JM, Rollinson D, Southgate VR. Schistosomiasis in the Republic of São Tomé and Principe: human studies.TransR Soc TropMed Hyg. 1994; 88:406-9.
Ripert C, Neves I, Appriou M et al. Epidemiology of certain endemic parasitic diseases in the town of Guadalupe (Republic of Sao Tome and Principe) I. Schistosomiasis intercalatum and intestinal worms. Bull Soc Pathol Exot. 1996; 89:252-8.
Belo S, Rompão H, Gonçalves L, Grácio MA. Prevalence, behavioral and social factors associated with Schistosoma intercalatum and geohelminth infections in São Tomé and Principe. Parassitologia. 2005;47:227-31.
Pampiglione S, Visconti S, Pezzino G. Human intestinal parasites in Subsaharan Africa. II. Sao Tome and Principe. Parassitologia. 1987; 29:15-25.
Engels D, Chitsulo L, Montresor A, Savioli L. The global epidemiological situation of schistosomiasis and new approaches to control and research. Acta Tropica. 2002; 82:139-146.
Mott KE. Contrasts in the control of schistosomiasis. Mem Inst Oswaldo Cruz. 1989; 84 Suppl 1:3-19.
Chu TB, Liao CW, D'Lamini P et al. Prevalence of Schistosoma haematobium infection among inhabitants of Lowveld, Swaziland, an endemic area for the disease. Trop Biomed. 2010; 27:337-42.
Opara KN, Udoidung NI, Ukpong IG. Genitourinary schistosomiasis among preprimary schoolchildren in a rural community within the Cross River Basin, Nigeria. J Helminthol. 2007; 81: 393-397.
Hsieh MH, Lin WY, Dai CY et al. Intestinal parasitic infection detected by stool examination in foreign laborers in Kaohsiung. Kaohsiung JMed Sci. 2010; 26:136-43.
Gryseels B, Polman K, Clerinx J, Kestens L. Human schistosomiasis. Lancet. 2006; 368: 1106-1118.
Knopp S, Mohammed KA, Speich B et al.Albendazole and mebendazole administered alone or in combination with ivermectin against Trichuris trichiura: a randomized controlled trial. Clin Infect Dis. 2010; 51: 1420-8.
Rompao H. Schistosomoses e helmintas intestinais em Sao Tome e Principe: Sao Tome. MSc Thesis. Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa: p. 59.
Tzanetou K, Astriti M, Delis V,Moustakas G, Choreftaki T, Papaliodi E, Sarri K, Adamis G. Intestinal schistosomiasis caused by both Schistosoma intercalatum and Schistosoma mansoni. Travel Med Infect Dis. 2010; 8:184-9.