Canine Visceral Leishmaniasis; A Seroepidemiological Survey in Jiroft District, Southern Kerman Province, Southeastern Iran in 2015
-
Mohammad Javad ABBASZADEH AFSHAR
,
Iraj SHARIFI
,
Mehdi BAMOROVAT
,
Mehdi MOHEBALI
,
Mohammad Saleh BAHREINI
,
Afsaneh NADERI
Abstract
Background: Domestic dogs have been implicated as the main reservoir host of Mediterranean type of visceral leishmaniasis (VL) that is endemic in some parts of Iran. This study was performed about role of dogs in canine VL (CVL) epidemiology in Jiroft District, south of Kerman Province, southeastern Iran.
Methods: Totally, 165 dogs including 100 stray and 65 sheepdogs were randomly selected. After complete clinical examination blood sample was taken from each dog. All the collected samples were examined following the serum separation by direct agglutination test (DAT) for detection of anti-Leishmania infantum antibodies. The titers of ≥1:320 were defined as positive.
Results: Overall, of 165 serum samples, 13 samples (7.9%) were positive by DAT at titers of ≥1:320. The seroprevalence was 11% among the stray dogs and 3% among the sheepdogs. There was no significant difference between stray and sheepdogs in CVL infection. The highest seroprevalence rate (14.3%) was found in seven-year old dogs.
Conclusion: The present finding indicates the role of stray and sheepdogs in CVL epidemiology in this area. Further investigations are needed to evaluate the status of VL infection in human subjects in this area.World Health Organization. Control of the leishmaniasis. Report of a meeting of the WHO Expert Committee on the Control of Leishmaniases. WHO Technical Report Series 949, Geneva, pp 1-187, 2014.
Bamorovat M, Sharifi I, Mohammadi MA et al. Canine visceral leishmaniasis in Ker-man, southeast of Iran: A seroepidemio-logical, histopathological and molecular study. Iran J Parasitol. 2014; 9: 342-349.
Mohebali M, Hajjaran H, Hamzavi Y et al. Epidemiological aspects of canine visceral leishmaniosis in the Islamic Republic of Iran. Vet Parasitol. 2005; 129: 243-251.
Cardoso LS, Rodrigues M, Santos H et al. Sero-epidemiological study of canine Leishmania spp. Infection in the municipality of Alijó (alto douro, Portugal). Vet Parasitol. 2004; 121: 21-32.
Desjeux P. Leishmaniasis: Current situation and new perspectives. Comp Immunol Microbiol Infect Dis. 2004;27: 305-318.
Mohebali M, Edrissian G, Nadim A et al. Application of direct agglutination test (DAT) for the diagnosis and seroepide-miological studies of visceral leishmaniasis in Iran. Iran J Parasitol. 2006; 1: 15-25.
Barati M, Sharifi I, Daie Parizi M, Fasihi Harandi M. Bacterial infections in children with visceral leishmaniasis: Observations made in Kerman province, southern Iran, between 1997 and 2007. Ann Trop Med Parasit. 2008;102: 635-641.
El Harith A, Slappendel R, Reiter I, Van Knapen F, De Korte P, Huigen E, Kolk A. Application of a direct agglutination test for detection of specific anti-leishmania antibodies in the canine reservoir. J Clin Microbiol. 1989; 27: 2252-2257.
Moshfe A, Mohebali M, Edrissian GhH, Zarei Z, Akhoundi B, Kazemi B, Jamshidi S, Mahmoodi M. Canine visceral leishmaniasis. Asymptomatic infected dogs as a source of infantum infection. Acta Trop. 2009; 112: 101-105.
Mostafavi M, Akhtardanesh B, Sharifi I, Kakooei S, Khedri J, Bamorovat M (2014). Seroprevalence of canine visceral leishmaniasis in southeast of Iran. J Parasit Dis. 2014; 38: 218-222.
Niknafs P, Daie Parizi M, Ahmadi A. Report of 40 cases of Kala-azar from Kerman province. J Kerman Univ Med Sci. 1994; 1: 30–37.
Moshfe A, Mohebali M, Edrissian GhH et al. Seroepidemiological study on canine visceral leishmaniasis in Meshkin-shahr district, Ardabil province, northwest of Iran during 2006-2007. Iran J Parasitol. 2008; 3: 1-10.
Mahmoudvand H, Mohebali M, Sharifi I et al. Epidemiological aspects of visceral leishmaniasis in Baft district, Kerman Province, southeast of Iran. Iran J Parasitol. 2011; 6: 1-11.
Asgari Q, Fakhar M, Motazedian M. Nomadic kala-azar in south of Iran. Iran J Public Health. 2006; 35: 85-86.
Sabzevari S, Razmi G, Naghibi A, Khoshnegah J. A serological study of Leishmania infantum in dogs of Khorasan Razavi province, Iran. J Parasitic Dis. 2013; 37: 189-191.
Hosseininejad M, Mohebali M, Hosseini F, Karimi S, Sharifzad S, Akhoundi B. Seroprevalence of canine visceral leishmaniasis in asymptomatic dogs in Iran. Iran J Vet Res. 2012; 13: 54-57.
Fakhar M, Motazedian MH, Asgari Q, Kalantari M. Asymptomatic domestic dogs are carriers of Leishmania infantum: Possible reservoirs host for human visceral leishmaniasis in southern Iran. Comp Clin Path. 2012; 21: 801-807.
| Files | ||
| Issue | Vol 13 No 1 (2018) | |
| Section | Original Article(s) | |
| Keywords | ||
| Canine visceral leishmani-asis Direct agglutination test (DAT) Iran | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
