Neospora caninum Suspects as One of the Most Important Causes of Abortion in Large Dairy Farms in Isfahan, Iran
Background: This study aimed to reveal the serological prevalence of Neospora caninum in large dairy farms in Isfahan Province, central Iran.
Methods: Serum samples were collected from 1500 cattle living in four large dairy farms in Isfahan Province, Iran during 2014-2015 and examined for anti N. caninum IgG antibodies. Overall, 113 serum samples were also collected from the dogs living in these areas; suspecting to be risk factors for this infection. All the serum samples were investigated to find IgG antibodies by using ELISA. Dogs' sera were also analyzed by indirect fluorescent antibody test.
Results: Totally, 395 out of 1500 bovine samples (26.33%) were positive for N. caninum: 34%, 21.61%, 23.03% and 29.01% in four investigated clusters (farms). Infection rate was significantly more in cows with the history of abortion. The infection rate in dogs was 17.69%: (20 out of 113).
Conclusion: The results show a high seroprevalence of the infection and possibly the role of the dogs in horizontal transmission of the infection.
Dubey JP, Schares G. Diagnosis of bovine neosporosis. Vet Parasitol. 2006; 140(1-2):1-34.
Davison HC, Otter A, Trees AJ. Significance of Neospora caninum in British dairy cattle determined by estimation of seroprevalence in normally calving cattle and aborting cattle. Int J Parasitol. 1999; 29(8):1189-94.
Moen AR, Wouda W, Mul MF et al. Increased risk of abortion following Neospora caninum abortion outbreaks: a retrospective and prospective cohort study in four dairy herds. Theriogenology. 1998; 49(7):1301-9.
Thurmond MC, Hietala SK.. Effect of congenitally acquired Neospora caninum infection on risk of abortion and subsequent abortions in dairy cattle. Am J Vet Res. 1997; 58(12):1381-5.
Paré J, Thurmond MC, Hietala SK. Congenital Neospora caninum infection in dairy cattle and associated calfhood mortality. Can J Vet Res. 1996; 60(2):133-9.
McAllister MM, Dubey JP, Lindsay DS et al. Dogs are definitive hosts of Neospora caninum. Int J Parasitol. 1998; 28 (9):1473-8.
Gondim LF, McAllister MM, Pitt WC et al. Coyotes (Canis latrans) are definitive hosts of Neospora caninum. Int J Parasitol. 2004; 34(2):159-61.
King JS, Slapeta J, Jenkins DJ et al. Australian dingoes are definitive hosts of Neospora caninum. Int J Parasitol. 2010; 40(8):945-50.
Dubey JP, Schares G, Ortega-Mora LM. Epidemiology and control of neosporosis and Neospora caninum. Clin Microbiol Rev. 2007; 20 (2):323-67.
Hosseininejad M, Hosseini F, Mosharraf M et al. Development of an indirect ELISA test using an affinity purified surface antigen (P38) for sero-diagnosis of canine Neospora caninum infection. Vet Parasitol. 2010; 171(3-4):337-42.
Schares G, Rauser M, Zimmer K, et al. Serological differences in Neospora caninum-associated epidemic and endemic abortions. J Parasitol. 1999; 85(4):688-94.
Schares G, Rauser M, Söndgen P et al. Use of purified tachyzoite surface antigen p38 in an ELISA to diagnose bovine neosporosis. Int J Parasitol. 2000; 30(10):1123-30.
Razmi GR, Mohammadi GR, Garrosi T et al. Seroepidemiology of Neospora caninum infection in dairy cattle herds in Mashhad area, Iran. Vet Parasitol. 2006;135(2):187-9.
Sadrebazzaz A, Haddadzadeh H, Esmailnia K et al. Serological prevalence of Neospora caninum in healthy and aborted dairy cattle in Mashhad, Iran. Vet Parasitol. 2004; 124(3-4):201-4.
Hajikolaei MR, Hamidinejat H, Ghorbanpoor M et al. Serological study of Neospora caninum infection in cattle from Ahvaz area, Iran. Int J Vet Res. 2008; 2 (1):63-6, 127.
Sevgili M, Atla MG, Keskin O. Seroprevalence of Neospora caninum in cattle in the province of anlurfa. Turk J Vet Anim Sci. 2005; 29 127-30.
Akca A, Gokce HI, Guy CS et al. Prevalence of antibodies to Neospora caninum in local and imported cattle breeds in the Kars province of Turkey. Res Vet Sci. 2005; 78 (2):123-6.
McAllister MM, Björkman C, Anderson-Sprecher R et al. Evidence of point-source exposure to Neospora caninum and protective immunity in a herd of beef cows. J Am Vet Med Assoc. 2000; 217(6):881-7.
Schares G, Bärwald A, Staubach C et al. P38-avidity-ELISA: examination of herds experiencing epidemic or endemic Neospora caninum-associated bovine abortion. Vet Parasitol. 2002; 106(4):293-305.
Jenkins MC, Caver JA, Björkman C et al. Serological investigation of an outbreak of Neospora caninum-associated abortion in a dairy herd in southeastern United States. Vet Parasitol. 2000; 94(1-2):17-26.
McAllister MM, Huffman EM, Hietala SK et al. Evidence suggesting a point source exposure in an outbreak of bovine abortion due to neosporosis. J Vet Diagn Invest. 1996; 8 (3):355-7.
Wouda W, Bartels CJ, Moen AR. Characteristics of Neospora caninum-associated abortion storms in dairy herds in The Netherlands (1995 to 1997). Theriogenology. 1999; 52(2):233-45.
Dijkstra T, Barkema HW, Eysker M et al. Natural transmission routes of Neospora caninum between farm dogs and cattle. Vet Parasitol. 2002; 105 (2):99-104.
Guy CS, Williams DJL, Kelly DF et al. Neospora caninum in persistently infected, pregnant cows: spontaneous transplacental infection is associated with an acute increase in maternal antibody. Vet Rec. 2001; 149 (15):443-9.
Wouda W, Moen AR, Schukken YH. Abortion risk in progeny of cows after a Neospora caninum epidemic. Theriogenology. 1998; 49(7):1311-6.
Anderson ML, Palmer CW, Thurmond MC et al. Evaluation of abortions in cattle attributable to neosporosis in selected dairy herds in California. J Am Vet Med Assoc. 1995; 207(9):1206-10.
Schares G, Peters M, Wurm R et al. The efficiency of vertical transmission of Neospora caninum in dairy cattle analyzed by serological techniques. Vet Parasitol. 1998; 80(2):87-98.
|Issue||Vol 12 No 3 (2017)|
|Neospora caninum Dairy farms Cattle Dogs Iran|
|Rights and permissions|
|This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.|