Onchocerciasis in the Upper Imo River Basin, Nigeria: Prevalence and Comparative Study of Waist and Shoulder Snips from Mesoendemic Communities
Abstract
Background: Onchocerciasis is endemic in the Imo River Basin, Nigeria. This study was aimed at assessing the prevalence and intensity of microfilaria of Onchocerca volvulus in the area.
Methods: A cross-sectional study was carried out in the Okigwe Local Government Area, Imo State, Nigeria. Two skin snips (one from the waist and another from the shoulder) were taken from 1024 individuals examined. The survey coverage was high (91.8% of the study population). An individual was considered mf positive if either of the waist or shoulder snips or both were mf positive. The SPSS for Windows package was used for entering and analysis of data.
Results: Thirty-seven percentage of those examined was positive for Onchocerca volvulus microfilariae (39.2% of males and 34.9% of females). The mf prevalence increased steadily with increasing age to reach 70.4% in the oldest age group. The overall mf Geometric Mean Intensity among mf positive individuals was 16 mf/skin snip and was significantly higher among males (18 mf/skin snip) than females (14 mf/skin snip) (p < 0.01). A scatter plot of microfilariae numbers in snips from the waist against numbers in snips from the shoulder of the same individuals, showed close correlation (Pearson's correlation coefficient = +0.90; p < 0.01), and those with mf intensities below 10 mf/snip had a more scattering tendency away from the regression line than those with higher mf intensities.
Conclusion: Onchocerciasis is a public health concern in the area. Perhaps, 10 mf/snip is critical intensity threshold for reliable sampling using corneo-scleral punch.
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