Evaluating the resistance of eimeria spp. Field isolates to anticoccidial drugs using three different indices.

  • F Arabkhazaeli Department of Pathobiology, Faculty of Veterinary Medicine, University of Tehran, Iran.
  • M Modrisanei Department of Animal and Poultry Health and Nutrition, Faculty of Veterinary Medicine, University of Tehran,Iran
  • S Nabian Department of Pathobiology, Faculty of Veterinary Medicine, University of Tehran, Iran
  • B Mansoori Department of Animal and Poultry Health and Nutrition, Faculty of Veterinary Medicine, University of Tehran,Iran
  • A Madani Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Iran
Keywords: Anticoccidial Sensitivity Test, Drug resistance, Eimeria, Global Index, Optimum Anticoccidial Activity

Abstract

 Background: In this study, the presence of resistance to diclazuril, amprolium+ethopabate and salinomycin, representing some of the commonest anticoccidials in Iran’s poultry industry, against three mixed Eimeria field isolates were investigated. Methods: Three Eimeria field isolates, collected from typical broiler farms in Iran, were propagated once, inoculated to 480 broilers, comprising 30 chicks in each treatment. The non-medicated or medicated diets containing one of the above mentioned anticoccidials were provided ad-lib. Drug ef-ficacy was determined using the Global index (GI), Anticoccidial Sensitivity Test (AST) and Opti-mum Anticoccidial Activity (OAA). Results: None of the field isolates were fully sensitive to the selected anticoccidials. All isolates showed reduced sensitivity/partial resistance to salinomycin. Resistance to amprolium+ethopabate was evident and partial to complete resistance was recorded for diclazuril. Conclusion: Limited efficacy of the selected anticoccidials is obvious. Considering the cost of conti-nuous use of anticoccidials in the field, altering the prevention strategy and rotation of the anticocci-dials with better efficacy, would prevent further economic losses induced by coccidiosis.

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How to Cite
1.
Arabkhazaeli F, Modrisanei M, Nabian S, Mansoori B, Madani A. Evaluating the resistance of eimeria spp. Field isolates to anticoccidial drugs using three different indices. Iran J Parasitol. 8(2):234-241.
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