A Diagnostic and Symptomatological Study on Trichomoniasis in Symptomatic Pregnant Women in Rafsanjan, South Central Iran in 2012-13

  • Azita MANSHOORI Department of Gynecology and Obstetrics, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  • Sakineh MIRZAEI Department of Gynecology and Obstetrics, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  • Zarrintaj VALADKHANI Department of Medical Parasitology, Pasteur Institute of Iran, Tehran, Iran
  • Mohammad KAZEMI ARABABADI Immunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  • Mohsen REZAEIAN Occupational Environment Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  • Nahid ZAINODINI Immunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  • Raza BAH¬RAMABADI Department of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  • Mohammad ZARE-BIDAKI Immunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Keywords: Trichomonas vaginalis, Diagnosis, Signs and symptoms, Iran


Background: Trichomonas vaginalis, the causative agent of trichomoniasis, is responsible for more than half of all sexually transmitted infections (STIs). The present study aimed to deter­mine the frequency of T. vaginalis infection and its clinical manifestations in sympto­matic pregnant women in the area based on four different diagnostic methods.Methods: A total of 162 pregnant women with at least one sign or symptom of vaginosis, referred to two gynecologic and obstetrics clinics in Rafsanjan City, south central Iran, were randomly selected in 2012-13. Through speculum examination of patients by gynecologists, clinical diagnosis determined, vaginal discharge were collected by using two sterile cotton swabs from the posterior fornix and vagina pH was measured. Samples were examined by three diagnostic methods including wet mount, culture in TYI-S-33 medium and polymerase chain reaction (PCR).Results: T. vaginalis was detected in 19.5%, 27.2%, 56.2% and 51.6% of subjects according to diagnostic methods of clinical diagnosis, wet mount, culture and PCR, respectively. There was statistically significant relationship between T. vaginalis infection and patients' age, gestational age, marriage age, residence, educational level, parity. The symptomatological pattern in the 91 women infected with T. vaginalis was as follows: leukorrhea, 96.7%; urine frequency, 65.9%; odorous secretion, 63.3%; urogenital itching and irritation, 53.8%; vagi­nal inflammation, 47.3%; dyspareunia, 39.6%; and dysuria, 16.5%.Conclusion: Our results indicated a high prevalence of T. vaginalis in symptomatic pregnant women, very low sensitivity and relative high specificity of clinical diagnosis and wet mount technique compared to culture and PCR, as well as that pregnancy increases the susceptibil­ity to the infection in a gestational age-dependent manner.


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How to Cite
MANSHOORI A, MIRZAEI S, VALADKHANI Z, KAZEMI ARABABADI M, REZAEIAN M, ZAINODINI N, BAH¬RAMABADIR, ZARE-BIDAKI M. A Diagnostic and Symptomatological Study on Trichomoniasis in Symptomatic Pregnant Women in Rafsanjan, South Central Iran in 2012-13. Iran J Parasitol. 10(3):490-497.
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