Can Giardia Infection Impair the Diagnostic Level of Fecal Calprotectin in Patients with Inflammatory Bowel Disease? A Case Report

  • Sara MOHAMMAD ALI GOL Behbood Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Hamed MIRJALALI Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Hamid ASADZADEH AGHDAEI Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterol-ogy and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Mohammad Reza ZALI Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Keywords: Inflammatory bowel dis-eases, Giardia intestinalis, Fecal calprotectin test

Abstract

Inflammatory bowel disease (IBD) is attributed to complex conditions of gastrointestinal tract that is frequently reported all over the world. Fecal calprotectin evaluation is described as a primary tool to screen IBD patients. There are reports showing the confounding role of some microbial agents in diagnostic levels of calprotectin. A 32-yr-old woman with symptoms like IBD/IBS (irritable bowel syndrome); admitted to IBD Clinic of Behbood Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Jan 2017 for evaluation of the level of fecal calprotectin. In spite of high level of calprotectin, trophozoite of Giardia intestinalis was observed in direct examination of stool sample. Microbial pathogens can lead to false elevation of fecal calprotectin and misdiagnosis of gastrointestinal patients suspected to IBD.

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Published
2018-09-24
How to Cite
1.
MOHAMMAD ALI GOL S, MIRJALALI H, ASADZADEH AGHDAEI H, ZALI MR. Can Giardia Infection Impair the Diagnostic Level of Fecal Calprotectin in Patients with Inflammatory Bowel Disease? A Case Report. IJPA. 13(3):505-9.
Section
Case Report(s)