Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 11 1 2016 03 14 24 29 Farnaz KHEIRANDISH Dept. of Parasitology and Mycology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Mohammad Hassan KAYEDI Dept. of Parasitology and Mycology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Behrouz EZATPOUR Dept. of Parasitology and Mycology, Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran Khatere ANBARI Dept. of Social Medicine, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Hamid Reza KARIMI ROUZBAHANI Deputy of Treatment, Lorestan University of Medical Sciences, Khorramabad, Iran Ali CHEGENI SHARAFI Dept. of Communicable Disease Control and Prevention, Deputy of Health, Lorestan University of Medical Sciences, Khorramabad, Iran Abolfazl ZENDEHDEL Dept. of Internal Medicine, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Negar BIZHANI Dept. of Parasitology and Mycology, School of Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad Bagher ROKNI Dept. of Parasitology and Mycology, School of Health, Tehran University of Medical Sciences, Tehran, Iran 2016 03 14 2016 03 14 Background: The purpose of this study was to perform seroepidemiological investigation for determining the status of human fasciolosis in Pirabad Village, Lorestan Province, western Iran. Methods: Blood samples were taken from residents of the village including 801 individuals. Sera were separated and stored at -20°C until used. The samples were analyzed using ELISA. Results: Anti-Fasciola antibodies were detected in 6 (0.7%) individuals. Difference between age, sex and drinking or swimming in the surface water with seropositivity to fasciolosis was not significant. Out of 7 shepherds, 1 (14.3%) was seropositive. Due to the small number of shepherds, comprehensive statistical inference in this regard cannot be done. Significant difference was detected between seropositivity to fasciolosis and consuming local freshwater vegetables during the last 6 months (P=0.001). Conclusion: Metacercariae carrying local freshwater plants might be the main source of contamination because consumption of these kinds of vegetables was confirmed by all participants. Awareness of local communities regarding the danger of freshwater plant consumption, through health education programs, will decrease the risk of infection. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/806 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/806/649