Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 10 4 2015 12 14 632 637 EN Ahmad HOSSEINI-SAFA Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran AND Dept. of Medical Parasitology AND Mycology School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Seyed Mohammad MOUSAVI Dept. of Medical Parasitology and Mycology Isfahan University of Medical Sciences, Isfahan, Iran Mehran BAHADORAN BAGH BADORANI Dept. of Medical Parasitology and Mycology Isfahan University of Medical Sciences, Isfahan, Iran Mehdi GHATREH SAMANI Dept. of Immunology Isfahan university of Medical Sciences, Isfahan, Iran Shayan MOSTAFAEI Dept. of Epidemiology and Biostatistics, School of public Health, Isfahan University of medical sciences, Isfahan, Iran Hossein YOUSOFI DARANI Dept. of Medical Parasitology and Mycology Isfahan University of Medical Sciences, Isfahan, Iran AND Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 2015 12 14 2015 12 14 Background: Human toxocariasis, a helminthozoonosis, is due to the migration of Toxocara species larvae into human organisms. Humans, especially children become infected by ingesting of embryonated eggs from soil, dirty hands, and raw vegetables. Seroprevalence of this infection is high in developed countries, especially in rural areas. The aim of this study was to investigate the seroepidemiology of Toxocariasis in chil­dren referred to the pediatric clinic of Imam Hossein hospital, Isfahan, Iran. Methods: In this cross sectional study the sera of children aged 5 to 15 years old, admit­ted to Imam Hossein Pediatric Hospital were collected during 2013-14. Then the sera were examined for anti Toxocara canis antibodies using commercial ELISA kit. Results: From 427 children, 196 (45.9%) were female and 231(54.1%) were male. 107(25.1%) were from rural and 320 (74.9%) were from urban area. Of them 129 (30.2%) were contacted with dog. One child (0.2%) had hypereosinophilia, 33 (7.7%) eosinophlia, and 6 (1.39%) were positive for T. canis IgG (two male and four female). Four of infected children with T. canis were from urban (1.25%) and two from rural areas (1.9%). There was no significant correlation between education of parents, gen­der, age, place of living and contact with dog with ELISA results test. Conclusion: Toxocariasis is prevalent in the children of Isfahan region.  Results sug­gest a low Toxocara exposure in children in this area. Therefore, more risk factors associ­ated with Toxocara exposure should be identified in the further investigation. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/665 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/665/546