Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 10 4 2015 12 14 517 522 EN Mojgan ARYAEIPOUR Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Eshrat Beigom KIA Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Zahra HEIDARI Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Zahra SAYYAD TALAIE Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad Bagher ROKNI Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Infectious Diseases, AJA University of Medical Sciences, Tehran, Iran 2015 12 14 2015 12 14 Background: Fascioliasis is a zoonotic disease of livestock and human caused by Fasciola species. Here in, the results of serological evaluation of fascioliasis in peo­ple referring to the School of Public Health, Tehran University of Medical Sci­ences during 2008-2014 are presented. Methods: Demographic characterizations, symptoms and eosinophil rate were registered for every patient. Using somatic antigen of Fasciola, ELISA was per­formed and the results were analyzed. Data of questioners were analyzed as well. Results: Among 206 applicants, 24.8% were seropositive for fascioliasis, included 21% female and 28.3% male. Mean range of age of patients was between 13 to 67 yr. The highest rate of seropositivity was found among 20-30 yr old patients. Most of the patients had hypereosinophilia. All patients had history of eating raw vegeta­bles, or drinking unsafe water. Patients were referring from different provinces of Iran, including Gilan, Mazandaran, Tehran, Ardabil, Khuzestan, Lorestan, North Khorasan, Kermanshah, Azerbaijan, Fars, Kordestan, Hamedan and Markazi. Conclusion: During recent years, variety of provinces in Iran, where patients with fascioliasis are referred, has been increased. Patients coming from Gilan and Mazanda­ran provinces were referred early after the onset of their symptoms. Most probably, physicians in Gilan and Mazandaran are more alert on fascioliasis than other provinces. Previous wrong diagnosis was more common among patients refer­ring from other provinces than Gilan and Mazandaran provinces. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/649 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/649/530