Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 9 2 2014 06 15 181 187 EN Mitra Sharbatkhori Department of Medical Parasitology & Mycology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran AND Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran. Yusef Dadi Moghaddam Social Security Organization, Gonbad, Iran. Abdol Sattar Pagheh Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Rasool Mohammadi Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Haleh Hedayat Mofidi School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. Saeedeh Shojaee Department of Medical Parasitology & Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 14 Background: Toxoplasma gondii is one of the most prevalent parasites of human and warm- blooded animals. Toxoplasmosis is important especially in two groups: pregnant women and immunocompromised patients. If women acquire the primary infection during the pregnancy, it would be life threatening or re-mains severe disorders for the fetus. This study was performed to evaluate the seroprevalence of T. gondii infection in pregnant women referred to Health Cen-ter in Gorgan City, Golestan Province, northern Iran. Methods: Serum samples were collected from pregnant women referred to Health Center in Gorgan City, south eastern Caspian Sea. Anti- Toxoplasma IgG and IgM antibodies were determined by commercially ELISA kits and the rela-tion of infection with socio-demographic and risk factors such as age, education, occupation, cat ownership, soil contact and some other factors was studied. Results: From 555 tested sera of pregnant women referred to Health Center in Gorgan, 39.8% had IgG antibodies against T. gondii and 3.4% were positive for IgM antibodies. A significant correlation was seen between T. gondii infection with age and soil contact. Conclusion: About 60% of pregnant women in Gorgan City are seronegative against T. gondii, so they should considered as at risk persons. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/415 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/415/329