Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 19 2 2024 06 09 Diagnosis and Treatment of Fasciola Infection with Endoscopic Retrograde Cholangiopancreatography (ERCP) in Ardabil, Northwest of Iran: Two Case Reports 255 259 EN Shabnam Asfaram Zoonoses Research Center, Ardabil University of Medical Sciences, Ardabil, Iran Behnam Sajedi Department of Internal Medicine, School of Medicine, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil, Iran Behnam Mohammadi-Ghalehbin Department of Microbiology and Immunology, School of Medicine, Ardabil University of Medical Sciences, Arda-bil, Iran 2024 01 30 2024 04 29 Here we report biliary fascioliasis in two women 27 and 54 years old from Ardabil Province, Iran who presented with nausea, anorexia, weight loss, and pain between shoulder blades. Endoscopic ultrasound showed distal common bile duct strictures (CBD) and a lesion in its proximal. Endoscopic retrograde cholangiopancreatography (ERCP) was performed and live parasites were diagnosed and successfully managed into the duodenal lumen. The clinical findings of the patient improved after the procedure. This report emphasizes that the prevalence of Fasciola in Ardabil is predictable and this infection could be simultaneously diagnosed and treated by the ERCP. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/4136 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/4136/1363