Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 18 2 2023 06 27 211 216 EN Dayane Moraes Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil Émelin Alves dos Santos Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil José Antônio Mendes Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil Ivanildes Barcelos Immunology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil João Alves de Souza Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil Maria do Rosário Gonçalves-Pires Parasitic Diagnosis Laboratory, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Mi-nas Gerais State, Brazil Julia Costa-Cruz Parasitic Diagnosis Laboratory, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Mi-nas Gerais State, Brazil Rosângela Rodrigues Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil 2021 11 26 2022 12 26 Background: Human cysticercosis (CC) is a global public health problem, especially in Latin America, including Brazil. We aimed to analyze the seroprevalence of CC among school-age children and adolescents. Methods: We analyzed the presence of specific IgG antibodies against Taenia solium metacestodes in 500 serum samples from elementary school children and adolescents in Jataí City, state of Goiás, Brazil. IgG antibodies against the antigenic extract of the parasite were detected and analyzed by ELISA, and specific peptides were identified by confirmatory Western Blotting test. Results: Of the 500 study participants, 205 (41%) were male, and 295 (59%) were female. Participants aged between 4 and 18 years (mean age 8.4 years). The percentage of serum samples reactive by ELISA was 37.2%. These samples were analyzed by Western Blotting, which confirmed that the seropositivity rate was 6.2% (95% CI 2.4–14.7) in 31 samples reactive for CC-specific bands, determined in serum samples from 18 male (5–11 years old) and 13 female (4–12 years old) students. Conclusion: The CC seroprevalence demonstrated in schoolchildren suggests that this parasitosis is endemic in the study area. Further investigations are necessary to clarify the local epidemiology of this parasitosis. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3511 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/3511/1289