Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 7 1 2012 03 15 36 44 EN H Turki Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran AND Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran S Zoghi Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran A A Mehrizi Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran S Zakeri Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran A Raeisi National Programme Manager for Malaria Control, Ministry of Health and Medical Education, Tehran, Iran AND Departement of Medical Entomology & Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran H Khazan Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran AA Haghdoost School of Public Health, Kerman University of Medical Science, Kerman, Iran 2015 10 03 Background: A successful malaria elimination program calls for enough attention to parasite carri­ers, especially asymptomatic malaria, as well as the diagnosis and treatment of clinical cases. Asymptomatic malaria is an infection that patients do not show any symptom; thus, these patients play critical role in the concept of an elimination program. The current investigation was con­ducted to evaluate the presence of these cases in Bashagard District, formerly a high malaria transmis­sion area in Hormozgan Province, Iran. Methods: Blood samples (n=500) were collected from symptomless individuals residing in Basha­gard to evaluate Plasmodium infection by using microscopic, serological and nested-PCR techniques. Results: Regarding the microscopic and nested-PCR analysis, no asymptomatic infection was detected among studied individuals. Totally, 1% of the studied population (5 of 500) had anti PvMSP-119-specific IgG antibody; however, only 0.2% (1 of 500) of the individuals was seroposi­tive to recombinant PfMSP-119, using ELISA. Conclusion: This study showed no asymptomatic malaria infection in the studied population; hence malaria elimination is feasible and can be successfully carried out in this region. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/218 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/218/217