Tehran University of Medical Sciences Iranian Journal of Parasitology 1735-7020 11 2 2016 12 21 279 283 Narges NAJAFI Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Eissa SOLEYMANI Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran Shahabeddin SARVI Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran Amirkeivan MAROFI Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Anahita NOSRATI Department of Pathology Research Center, Mazandaran University of Medical Sciences, Sari, Iran Alireza DAVOODI Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran 2016 07 02 2016 07 02 Strongyloides stercoralis is a soil-transmitted helminth (STH) widespread in various part of the world. A 78-yr-old peasant diabetic female from Mazandaran Province northern Iran, was admitted to Infection Department of the Razi Hospital in city of Qaemshahr, north of Iran complaining about abdominal skin rash, pruritus, itching, anorexia, nausea, vomiting, dysuria and cough. This patient had cutaneous migration effects of S. stercoralis larvae in her abdominal skin (larva currents and urticaria). Lung CT without contrast demonstrates bilateral diffuse ground glass opacity draws attention. Upper gastrointestinal endoscopy revealed gastro esophageal reflux with antral gastritis. Duodenal endoscopy showed unusual mucosa and a biopsy from it sent to the pathology laboratory. Histopathology of duodenal bulb and duodenum biopsy showed mild villous atrophy and S. stercoralis infection. The patient was treated with albendazole and clinical sings improved completely after treatment. Strongyloidiasis should be care­fully considered by clinicians who practice in endemic areas. Clinicians must keep a high level of skepticism for patients from endemic area. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1072 https://ijpa.tums.ac.ir/index.php/ijpa/article/download/1072/701