Seroprevalence of Human Hydatidosis Using ELISA Method in Qom Province, Central Iran

  • A Rakhshanpour Zoonoses Research Center, Dept. of Medical Parasitology and Mycology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran AND Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran,Iran
  • M Fasihi Harandi Zoonoses Research Center, Dept. of Medical Parasitology and Mycology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  • SS Moazezi Iranian Blood Transfusion Organization, Tehran, Iran
  • MT Rahimi Department of Medical Parasitology and Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  • M Mohebali Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran
  • GhH Mowlavi Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran
  • Z Babaei Zoonoses Research Center, Dept. of Medical Parasitology and Mycology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  • M Ariaeipour Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Z Heidari Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • MB Rokni Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran
Keywords: Cystic Echinococcosis, ELISA, Epidemiology, Risk factor, Iran

Abstract

Background: The objective of this study was to determine the prevalence of cystic echinococcosis (CE) in Qom Province, central Iran using ELISA test.Methods: Overall, 1564 serum samples (800 males and 764 females) were collected from selected subjects by randomized cluster sampling in 2011-2012. Sera were analyzed by ELISA test using AgB. Before sampling, a questionnaire was filled out for each case. Data were analyzed using Chi-square test and multivariate logistic regression for risk factors analysis.Results: Seropositivity was 1.6% (25 cases). Males (2.2%) showed significantly more positivity than females (0.9%) (P= 0.03). There was no significant association between CE seropositivity and age group, occupation, and region. Age group of 30-60 years encompassed the highest rate of positivity. The seropositivity of CE was 2.1% and 1.2% for urban and rural cases respectively. Binary logistic regression showed that males were 2.5 times at higher risk for infection than females.Conclusion: Although seroprevalence of CE is relatively low in Qom Province, yet due to the impor­tance of the disease, all preventive measures should be taken into consideration.

References

Torgerson PR, Deplazes P. Echinococcosis: diagnosis and diagnostic interpretation in population studies. Trends Parasitol. 2009; 25:164-70.

Budke CM, Deplazes P, Torgerson PR. Global socioeconomic impact of cystic echinococcosis. Emerg Infec Dis. 2006; 12:296-303.

Rokni MB. Echinococcosis /hydatidosis in Iran. Iranian J Parasitol. 2009; 4:1-16.

Rokni MB. The present status of human helminthic diseases in Iran. Ann Trop Med Parasitol. 2008; 102:283-95.

Rokni MB, Aminian B. Evaluation of the Enzyme-linked Immuno-electro Transfer Blot (EITB) technique using hydatid cyst antigens B/5 and total IgG antibodies in laboratory diagnosis of human hydatidosis. Pak J Med Sci. 2006; 22:127-31.

Baharsefat M, Massoud J, Mobedi I, Farahnak A, Rokni M. Seroepidemiology of cystic echinococcosis in referred patients to health centers in Golestan Province using ELISA and IFA. Iranian J Parasitol. 2007; 2 20-4.

Haniloo A, Badali H, Esmaeil Zadeh AR. Seroepidemiological study of hydatidosis in Zanjan, Islam-Abad, 2002. Journal of Zanjan University of Medical Sciences & Health Services. 2004;12:41-46.

Arbabi M, Hooshyar H. Survey of echinococcosis and hydatidosis in Kashan region, central Iran. Iranian J Publ Health. 2006; 35:75-81.

Heidari Z, Mohebali M, Aryayipour M, Eshraghian MR, Kia EB, Shodajei S, Abdi J, Rakhshanpour A, Rokni MB. Seroepidemiological study of human hydatidosis in Meshkinshahr district, Ardabil province, Iran. Iranian J Parasitol. 2011; 6 (3):19-25.

Aflaki A, Ghaffarifar F, Dalimi Asl A. Seroepidemiological survey of hydatidosis by Dot- ELISA in Ilam province. Journal of Medical Science of Modarres. 2005;8:1-6.

Rafiei A, Hemadi A, Maraghi S, Kaikhaei B, Craig PS. Human cystic echinococcosis in nomads of southwest Islamic Republic of Iran. Eastern Mediterr Health J. 2007;13:41-48.

Harandi MF, Moazezi SS, Saba M, Grimm F, Kamyabi H, Sheikhzadeh F, Sharifi I, Deplazes P. Sonographical and serological survey of human cystic echinococcosis and analysis of risk factors associated with seroconversion in rural communities of Kerman, Iran. Zoonoses and Public Health, 2011; 58: 582–588.

Ahmadi NA, Hamidi M. A retrospective analysis of human cystic echinococcosis in Hamadan province, an endemic region of Iran. Ann Trop Med Parasitol. 2008; 102:603-609.

Ghaffari S. Survey of surgery cases of hydatidosis in three educationaltreatment centers of Babol. Journal of Babol University of Medical Sciences. 1999; 1(1):27-33.

Tavakoli HR, Bahonar AR, Jonidi NA. Epidemiology of hydatidosis in Iran during 2002-2006. Iran J Infec Dis Trop Med. 2008; 13 (42):67-71.

Haniloo A, Massoud J, Rokni MB. Evaluation and comparison of antigen B-ELISA and antigen B-immunoblotting in immunodiagnosis of cystic hydatid disease. Pak J Med Sci. 2005;21(3):352-356.

Sadjjadi SM, Abidi H, Sarkari B, Izadpanah A, Kazemian S. Evaluation of Enzyme Linked Immunosorbent Assay, Utilizing Native Antigen B for Serodiagnosis of Human Hydatidosis. Iran J Immunol. 2007; 4 (3):167-172.

Yang YR, Craig PS, Vuitton DA, Williams GM, Sun T, Liu TX, et al. Serological prevalence of echinococcosis and risk factors for infection among children in rural communities of southern Ningxia, China. Trop Med Int Health. 2008; 13(8): 1-9.

How to Cite
1.
Rakhshanpour A, Fasihi Harandi M, Moazezi S, Rahimi M, Mohebali M, Mowlavi G, Babaei Z, Ariaeipour M, Heidari Z, Rokni M. Seroprevalence of Human Hydatidosis Using ELISA Method in Qom Province, Central Iran. IJPA. 7(3):10-5.
Section
Articles