Detection of Opisthorchis viverrini Infection among the ASEAN Population in Thailand Using a Verbal Screening Test and Fecal Concentrator Kit

  • Natthawut KAEWPITOON Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand
  • Soraya KAEWPITOON Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand School of Family Medicine and Community Medicine, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand
  • Thirayu MEERERKSOM Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Business Computer, Faculty of Management Science, Nakhon Ratchasima Rajabhat University, Nakhon Ratchasima, Thailand
  • Siwawich CHAN-ARAN Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Business Computer, Faculty of Management Science, Nakhon Ratchasima Rajabhat University, Nakhon Ratchasima, Thailand
  • Wararat SANGWALEE Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand
  • Jun NORKAEW Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand
  • Jirayu CHUATANAM Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand
  • Jirawoot KUJAPAN Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Public Health, Faculty of Liberal Arts and Science, Roi-Et Rajabhat University, Roi-Et, Thailand
  • Natnapa PADCHASUWAN Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Dept. of Health Education, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand
  • Taweesak TONGTAWEE Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand
  • Likit MATRAKOOL Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand
  • Ryan LOYD Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand School of Family Medicine and Community Medicine, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand
  • Parichart WAKKHUWATTHAPONG Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Keywords: Opisthorchis viverrini, ASEAN population, Thailand, Verbal screening test, Fecal concentrator kit

Abstract

Background: Opisthorchis viverrini is a serious health problem in Southeast Asia. The infection is associated with cholangiocarcinoma. Therefore, this study was aimed to detect O. viverrini infections among the ASEAN population in Thailand.Methods: A cross-sectional study was conducted among 249 individuals from ASEAN populations in Thailand including Thai, Laotian, Cambodian, and Myanmar. Participants were screened using the O. viverrini verbal screening test (OvVST). Fecal samples were processed by the mini-parasep sf parasite fecal concentrator.Results: The infection rate of O. viverrini was 27.21%. The majority of infections was detected in females, in the age group 31-40 yr old, in the primary school education level, and in the occupation of labor. By country, O. viverrini infection was detected more often in the Lao PDR (30.77%). In screening for O. viverrini infection, OvVST had a high sensitivity (93.48%), specificity (86.70%), NPV (98.32%), and accuracy (87.95%). The PPV was 61.43% for OvVTS. The observed agreement was substantial for OvVST (k-value = 0.64).Conclusion: O. viverrini infections are still detected in ASEAN countries therefore large scale active surveillance is required. OvVST had a high sensitivity, specificity, and accuracy for screening the risk groups for O. viverrini.

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Published
2018-06-25
How to Cite
1.
KAEWPITOON N, KAEWPITOON S, MEERERKSOM T, CHAN-ARAN S, SANGWALEE W, NORKAEW J, CHUATANAM J, KUJAPAN J, PADCHASUWAN N, TONGTAWEE T, MATRAKOOL L, LOYD R, WAKKHUWATTHAPONG P. Detection of Opisthorchis viverrini Infection among the ASEAN Population in Thailand Using a Verbal Screening Test and Fecal Concentrator Kit. IJPA. 13(2):258-66.
Section
Case Report(s)