Iranian Journal of Parasitology 2018. 13(2):258-266.

Detection of Opisthorchis viverrini Infection among the ASEAN Population in Thailand Using a Verbal Screening Test and Fecal Concentrator Kit
Natthawut KAEWPITOON, Soraya KAEWPITOON, Thirayu MEERERKSOM, Siwawich CHAN-ARAN, Wararat SANGWALEE, Jun NORKAEW, Jirayu CHUATANAM, Jirawoot KUJAPAN, Natnapa PADCHASUWAN, Taweesak TONGTAWEE, Likit MATRAKOOL, Ryan LOYD, Parichart WAKKHUWATTHAPONG

Abstract


Background: Opisthorchis viverrini is a serious health problem in Southeast Asia. The infection is associated with cholangiocarcinoma. Therefore, this study was aimed to detect O. viverrini infections among the ASEAN population in Thailand.

Methods: A cross-sectional study was conducted among 249 individuals from ASEAN populations in Thailand including Thai, Laotian, Cambodian, and Myanmar. Participants were screened using the O. viverrini verbal screening test (OvVST). Fecal samples were processed by the mini-parasep sf parasite fecal concentrator.

Results: The infection rate of O. viverrini was 27.21%. The majority of infections was detected in females, in the age group 31-40 yr old, in the primary school education level, and in the occupation of labor. By country, O. viverrini infection was detected more often in the Lao PDR (30.77%). In screening for O. viverrini infection, OvVST had a high sensitivity (93.48%), specificity (86.70%), NPV (98.32%), and accuracy (87.95%). The PPV was 61.43% for OvVTS. The observed agreement was substantial for OvVST (k-value = 0.64).

Conclusion: O. viverrini infections are still detected in ASEAN countries therefore large scale active surveillance is required. OvVST had a high sensitivity, specificity, and accuracy for screening the risk groups for O. viverrini.

Keywords


Opisthorchis viverrini, ASEAN population, Thailand, Verbal screening test, Fecal concentrator kit

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